一、导师情况:
1、硕士生导师:2004年起担任复旦大学硕士生导师
2018年起担任同济大学硕士生导师.
Master Instructor, Fudan University, 2004
Master Instructor, Tongji University, 2018
2、博士生导师: 2011年起担任复旦大学博士生导师
2018年起担任同济大学博士生导师.
PhD Tutor, Fudan University, 2011
PhD Tutor, Tongji University, 2018
二、人才培养情况:
美国斯坦福大学访问学者
入选上海市卫生优秀学科带头人培养计划、浦江人才计划,曾担任“上海市医学重点专科”、复旦大学“985优势学科建设”学科带头人。
1、Visiting Scholar, Stanford University
2、Shanghai New Hundred Talents Program(Shanghai Excellent Academic Leadership Training Program)
3、Pujiang Talents Program in Shanghai.
4、Director of “Shanghai Key Medical Training Department”
5、Director of “985 Advantage Medical Training Department of Fudan University”
三、学术兼职:
上海市医学会神经病学专业委员会第六、七、八届委员,脑卒中专业委员会研究组副组长,中国医师协会中西医结合神经病学专业委员会委员,上海市中西医结合神经病学专委会常委,上海市医师协会神经病学专委会委员,是《中华脑血管病杂志》等多个杂志的编委。美国神经科学学会SFN会员、神经病学会AAN会员、卒中学会ASA会员。
1、Committee Member :Shanghai Medical Association of Neurology(Sixty-seventh- Eighth)。
2、Vice Director of Research Group, Shanghai Medical Association of Stroke
3、Committee Member :Chinese Medical Doctor Association of Integrated Traditional and Western Medicine in Neurology
4、Standing committee member:Shanghai Integrated Traditional and Western Medicine in Neurology
5、Committee Member :Shanghai Medical Doctor Association of Neurology
6、Member: Society for Neuroscience
7、Member: American Association of Neurology
8、Member: American Stroke Association
1、研究方向:分别为脑血管病临床研究、缺血脑保护基础研究和信息化医疗
(1)、在脑血管病临床上,主要在急性脑梗塞超早期溶栓治疗的影像评估、危险因素评估与干预、远程康复等方面做了一系列研究工作;同时在脑动脉硬化、脑动脉狭窄的无创检查与DSA血管内评估、脑梗塞超早期血管内治疗、脑动脉狭窄的血管内介入治疗方面做了大量的临床及研究工作。
(2)、在脑保护研究上,先后获得“国家自然科学基金”资助2项,并获得上海市科委重点项目、上海市卫生发展基金项目等各级研究课题9项,参与美国NIH、AHA等项目3项,在此领域发表SCI论文22篇,累积被引用800多次,先后多次参加SFN、AAN、ISC等国际会议,并做大会交流。在“内源性脑保护”研究方面在国际上处于被跟踪地位。
(3)在信息化医疗方面,做为技术负责人承担了上海市战略性新兴产业重大项目,同时承担了4个上海市科委产学研项目,是国家物联网重大专项首席专家,并获“医疗信息化标准”项目资助,获得远程康复的首个Clinical trial Number,主编有《健康物联网》专著
2、承担研究项目:2009年起做为项目负责人或项目申报/完成人承担各类研究项目20项(不包括参研项目),总研究经费3300多万元。包括国家自然科学基金2项,上海市战略性新兴产业重大项目、上海市科委、上海市经信委等项目14项。
3、发表论文:发表中文论文50余篇、SCI论文24篇(其中第一作者4篇,通迅作者15篇)。
1、Research Subject:
(1) Stroke Clinical Research:
Image research in stroke.
Risk factor evaluation and intervention of Stroke.
Remote rehabilitation of stroke.
Super acute thrombolytic therapy for acute cerebral infarction.
Noninvasive Assessment research in cerebral arteriosclerosis and cerebral artery Stenosis .
DSA and endovascular treatment for acute ischemic stroke and cerebral artery stenosis
(2) Research in inner cerebral protection:
Our group focused in inner cerebral protection research. We have received 2 grants from the National Natural Science Foundation of China, and obtained 9 research projects from Shanghai Science and Technology Commission and Shanghai Health Development Fund Project, participating 3 grants from NIH and AHA. Our group have published 22 SCI papers and its be citied more than 800 times.
(3) Medical information research:
In this research area, our group have received 1 key major project from shanghai government and 4 grants from Shanghai Municipal Science and Technology Commission. As a major special expert of the National Internet of Things, we received the “Medical Informatization Standards” project. We have obtained the Clinical trial Number for remote rehabilitation, and edited a book-- “Health Internet of Things”
2、Research Grants:
From 2009, as a project leader or project declaration/completion person, I have undertake 20 research projects, with a total research budget of more than 33 million RMB. Including 2 National Natural Science Foundation of China, and other grants from Shanghai Science and Technology Commission, Shanghai Economic and Trade Commission and fudan University.
3、Published Papers:
published more than 50 Chinese papers and 24 SCI papers (including 4 first authors and 15 communication authors).
(1)Ren C, Gao X,Steinberg, Zhao H*. Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning. Neuroscience. 2008;151(4):1099-103.
(2)Ren C, Gao X, Niu G, Yan Z, Chen X, Zhao H*. Delayed Postconditioning Protects against Focal Ischemic Brain Injury in Rats. PLoS ONE. 2008; 3(12): e3851.
(3)Zhang H, Ren C, Gao X, Takahashi T, Spolsky RM, Steinberg GK, Zhao H*. Hypothermia blocks beta-catenin degradation after focal ischemia in rats.Brain Res. 2008 ;1198:182-7.
(4)Gao X,Ren C, Zhao H*. Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning.J Neurosci Res. 2008 ;86(11):2505-11.
(5) Zhang H,Gao X,Yan Z, Ren C, Shaimohata T, Steinberg GK, Zhao H*. Inhibiting caspase-3 activity blocks beta-catenin degradation after focal ischemia in rat.Neuroreport. 2008 ;19(8):821-4.
(6) Bai YH, Ren CC*, Gong XR, Meng LP.A maternal hereditary deafness pedigree of the A1555G mitochondrial mutation, causing aminoglycoside ototoxicity predisposition.J Laryngol Otol. 2008 Oct;122(10):1037-41.
(7) Ryu EK, Wu Z, Chen K, Lazarus LH, Marczak ED, Sasaki Y, Ambo A, Salvadori S, Ren C , Zhao H, Balboni G, Chen X*. Synthesis of a Potent and Selective (18)F-Labeled delta-Opioid Receptor Antagonist Derived from the Dmt-Tic Pharmacophore for Positron Emission Tomography Imaging. J Med Chem. 2008 ;51(6):1817-23.
(8)Ren C, Yan Z, Wei D, Gao X, Chen X, Zhao H*. Limb remote postconditioning protects against focal ischemia in rats. Brain Res. 2009 Sep 8;1288:88-94.
(9)Wei D, Ren C,Chen X, Zhao H*(Co-first author). The Chronic Protective Effects of Limb Remote Preconditioning and the Underlying Mechanisms Involved in Inflammatory Factors in Rat Stroke. PLoS ONE,2012;7(2):e30892.
(10)Jin Z, Shi L, Wang YJ, Yang LG, Shi YH, Shen LW, Ren CC*.Prevalence of headache among children and adolescents in Shanghai, China.J Clin Neurosci. 2013 ;20(1):117-21.
(11)Zhao H*, Ren C, Chen X, Shen J. From Rapid to Delayed and Remote Postconditioning: The Evolving Concept of Ischemic Postconditioning in Brain Ischemia. Curr Drug Targets. 2012 ; 13(2): 173–187.
(12)Chen J,Jin W, Dong WS, Jin Y, Qiao FL, Zhou YF, Ren CC(corresponding author). Effects of Home-based Telesupervising Rehabilitation on Physical Function for Stroke Survivors with Hemiplegia: A Randomized Controlled Trial. Am J Phys Med Rehabil. Am J Phys Med Rehabil. 2017 Mar;96(3):152-160.
(13)Jin W, Xu W, Chen J, Zhang X, Shi L, Ren C(corresponding author). Remote limb preconditioning protects against ischemia-induced neuronal death through ameliorating neuronal oxidative DNA damage and parthanatos. J Neurol Sci. 2016 Jul 15;366:8-17.
(14)Jin W, Xu W, Chen J, Zhang X, Shi L, Ren C(corresponding author).Adenosine kinase facilitated astrogliosis-induced cortical neuronal death in+D5 traumatic brain injury. J Mol Histol. 2016 Jun;47(3):259-71.
(15) Xu W, Jin W, Zhang X, Chen J, Ren C(corresponding author).Remote Limb Preconditioning Generates a Neuroprotective Effect by Modulating the Extrinsic Apoptotic Pathway and TRAIL-Receptors Expression.Cell Mol Neurobiol. 2017 Jan;37(1):169-182.
(16)Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC(corresponding author).Telerehabilitation Approaches for Stroke Patients: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2660-8.
(17)Jin W, Chen J, Shi F, Yang W, Zhang Y, Liu Y, Dong W, Jin Y, Ma W, Ma Z, Min X, Jin Y, Gu Y, Ren C(corresponding author).Home-based tele-supervising rehabilitation for brain infarction patients (HTRBIP): study protocol for a randomized controlled trial. Trials. 2015 Feb 25;16:61.
(18)Duan S, Zhang S, Li L, Ren C(corresponding author)Xie J.Cariod antery intima-media thickness associated with prognosis of intracranial branch atheromatous disease..Int J Neurosci. 2016 Apr 21:1-7.
(19)Duan S, Shao G, Yu L, Ren C(corresponding author).Angiogenesis contributes to the neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats. Int J Neurosci. 2015;125(8):625-34.
(20) Guo T, Li H, Lv Y, Lu H, Niu J, Sun J, Yang GY, Ren C, Tong S(Co-corresponding author). Pulsed Transcranial Ultrasound Stimulation Immediately After The Ischemic Brain Injury is Neuroprotective.IEEE Trans Biomed Eng. 2015 Oct;62(10):2352-7.
(21)Liu M, Chen J,Zhang S,Ren C.(corresponding author) Downregulation of lipocalin-2 and Bim expression after remote limb preconditioning in the ischemic rat brain. Brain Res. 2018;1679:1-9.
(22)Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC (corresponding author).Three Stages of Evolution in the Treatment of Acute Ischemic Stroke: Stroke Unit Care, Intravenous Thrombolysis and Endovascular Therapy. Journal of Neurology and Neurological Disorders. J Neurol Neurol Disord 3(3): 306.
(23)Chen J, Liu M, Sun D, Jin Y, Wang T, Ren C(corresponding author).Effectiveness and neural mechanisms of home-based telerehabilitation in patients with stroke based on fMRI and DTI: A study protocol for a randomized controlled trial. Medicine . 2018 Jan;97(3):e9605.
(24)Chen J, Jin W, Dong WS, Jin Y, Qiao FL, Zhou YF, Ren CC(corresponding author).Effects of Home-based Telesupervising Rehabilitation on Physical Function for Stroke Survivors with Hemiplegia: A Randomized Controlled Trial.Am J Phys Med Rehabil. 2017 Mar;96(3):152-160.