同济大学医学与生命科学部副主任、脊柱脊髓损伤再生修复教育部重点实验室主任、上海市重中之重脊柱脊髓疾病研究中心主任、同济大学附属同济医院骨科主任及脊柱外科主任、同济大学脊髓脊柱损伤研究所所长,担任国家重点研发计划首席科学家、国家“重点领域创新团队”负责人,以及国家临床重点专科、上海市重中之重重点学科骨科及上海市临床重点专科脊柱外科学科带头人。
兼任国际神经修复学会(IANR)理事与中国区副主任、国际矫形与创伤外科学会(SICOT)中国部骨科基础学会常务委员、中国研究型医院学会常务理事、教育部临床医学教学指导委员会委员、中国研究型医院神经转化研究专委会副主任委员、中国研究型医院学会神经再生与修复专业委员会副主任委员,中国康复医学会骨质疏松预防与康复专业委员会副主任委员、中国医师协会神经修复专委会常务委员、中国医师协会骨科医师分会常务委员、中华医学会创伤专委会委员、中国医师协会骨科医师分会委员兼脊柱工作委员会委员,上海医学会理事、上海医师协会理事、上海市医师协会骨科分会副会长、上海医学会骨科专科委员会委员、上海医学会骨科委员会微创学组副组长。
《Neural regenration research(NRR)》编委、《Chinese Medical Journal》编委、《中华创伤杂志》副总编辑、《中华医学杂》志特约编委、《中华外科杂志》通讯编委、《中华骨科杂志》通讯编委。
Vice Director of the Department of Medicine and Life Sciences at Tongji University, Director of the Key Laboratory of Spinal Cord Injury Regeneration and Repair at the Ministry of Education, Director of the Shanghai Key Spinal Cord Disease Research Center, Director of Orthopedics and Spinal Surgery at Tongji Hospital Affiliated to Tongji University, Director of the Institute of Spinal Cord and Spinal Injury at Tongji University, Chief Scientist of the National Key R&D Program, Head of the National Key Field Innovation Team, and Leader of the National Clinical Key Specialty, Shanghai Key Discipline Orthopedics, and Shanghai Clinical Key Specialty Spinal Surgery.
Serving as a member of the International Association of Neurological Repair (IANR) and Deputy Director of the China region, as well as the International Society of Orthopaedic and Traumatology (SICOT) Executive Committee Member of the Chinese Orthopedic Foundation Society, Executive Director of the Chinese Research Hospital Association, Member of the Clinical Medicine Teaching Guidance Committee of the Ministry of Education, Vice Chairman of the Chinese Research Hospital Neurotransformation Research Committee, Vice Chairman of the Chinese Research Hospital Association Neuroregeneration and Repair Professional Committee, Vice Chairman of the Chinese Rehabilitation Medicine Association Osteoporosis Prevention and Rehabilitation Professional Committee, Executive Committee Member of the Chinese Medical Association Neurorepair Professional Committee, Executive Committee Member of the Chinese Medical Association Orthopedic Physician Branch, Member of the Chinese Medical Association Trauma Professional Committee, Member of the Chinese Medical Association Orthopedic Physician Branch and Spinal Work Committee, Director of the Shanghai Medical Association, Director of the Shanghai Medical Association, Vice President of the Orthopedic Branch of the Shanghai Medical Association, Member of the Orthopedic Specialty Committee of the Shanghai Medical Association Deputy Leader of the Minimally Invasive Group of the Orthopedic Committee of the Shanghai Medical Association.
Editorial Board Member of Neural Regression Research (NRR), Editorial Board Member of Chinese Medical Journal, Deputy Editor in Chief of Chinese Journal of Trauma, Special Editorial Board Member of Chinese Medical Journal, Corresponding Editorial Board Member of Chinese Journal of Surgery, and Corresponding Editorial Board Member of Chinese Journal of Orthopedics
入选国家高层次人才特殊支持计划(国家“万人计划”)科技创新领军人才、国家百千万人才工程人选、教育部新世纪优秀人才、上海市领军人才、新一轮上海市卫生系统优秀学科带头人、上海市优秀学科带头人等;主持国家重点研发计划2项、国家自然科学基金重点2项等项目共计28项。
发表论文300余篇,其中Cell、Nature Medicine、Advanced Materials 、Advanced Science、Signal Transduction and Targeted Therapy等SCI、EI收录论文130余篇,中华核心期刊30余篇;主编著作5部,参编著作10余部;获批专利46项,其中发明专利22项,美国发明专利3项。
作为第一完成人获得中国康复医学会科学技术奖一等奖、华夏医学科技奖一等奖、上海市自然科学奖一等奖、上海市科技进步奖一等奖、上海医学科技奖一等奖、上海康复医学科技奖一等奖、上海医学科技奖成果推广奖、上海市优秀发明奖金奖等省部级奖励10余项。
近年获国家百千万人才工程人选、国家有突出贡献中青年专家、国务院特殊津贴专家、霍英东教育教学奖、2023年度推动行业前行的力量“十大医学影响力专家”、首届上海杰出人才、上海医学发展杰出贡献奖、上海市科技精英、上海市先进工作者、上海市仁心医者•上海市仁心医师奖、上海市五一劳动奖章、上海市模范教师、霍英东教育教学奖二等奖手等荣誉。
Selected as a leading talent in scientific and technological innovation under the National Special Support Program for High level Talents (National "Ten Thousand Talents Program"), a candidate for the National Hundred, Thousand, and Ten Thousand Talents Project, an outstanding talent of the Ministry of Education in the new century, a leading talent in Shanghai, an outstanding discipline leader in the new round of Shanghai's health system, and an outstanding discipline leader in Shanghai; Hosted a total of 28 projects, including 2 national key research and development programs and 2 key projects funded by the National Natural Science Foundation of China.
Published over 300 papers, including Cell、Nature Medicine、Advanced Materials 、Advanced Science、Signal Transduction and Targeted Therapy More than 130 papers have been included in SCI and EI, and over 30 papers have been published in Chinese core journals; Chief editor of 5 works and co editor of over 10 works; Obtained 46 patents, including 22 invention patents and 3 US invention patents.
As the first author, I have won more than 10 provincial and ministerial level awards, including the first prize of China Rehabilitation Medicine Association Science and Technology Award, the first prize of Huaxia Medical Science and Technology Award, the first prize of Shanghai Natural Science Award, the first prize of Shanghai Science and Technology Progress Award, the first prize of Shanghai Medical Science and Technology Award, the first prize of Shanghai Rehabilitation Medicine Science and Technology Award, the achievement promotion award of Shanghai Medical Science and Technology Award, and the gold award of Shanghai Excellent Invention Award.
In recent years, he has won many honors, such as candidates for the National Hundred and Ten Thousand Talents Project, young and middle-aged experts with outstanding contributions, experts with special subsidies from the State Council, Huo Yingdong Education and Teaching Award, "Top Ten Medical Influential Experts" in 2023, the first Shanghai Outstanding Talents, Shanghai Medical Development Outstanding Contribution Award, Shanghai Science and Technology Elite, Shanghai exemplary individual, Shanghai Benevolent Doctor • Shanghai Benevolent Doctor Award, Shanghai May Day Labor Medal, Shanghai Model Teachers, and the second prize winner of Huo Yingdong Education and Teaching Award.
代表性论文
1. Xu X#, Gao F#, Chen Q#, Chen B#, Liang W, Huang R, Liu Y, Liu Z, Zhu Y, Lin G, Ma B, Yang L, Gao S*, Zhu R*, Cheng L*. F-box/LRR-repeat protein 12 reorchestrated microglia to inhibit scarring and achieve adult spinal cord injury repair. Signal Transduct Target Ther. 2025 Aug 20;10(1):259
2. Hongxing Hu, Zhaojie Wang, Huiyi Yang, Yuxin Bai, Rongrong Zhu*, Liming Cheng*. Hypoxic Preconditional Engineering Small Extracellular Vesicles Promoted Intervertebral Disc Regeneration by Activating Mir-7-5p/NF-Κb/Cxcl2 Axis. Advanced Science . 2023 Oct 23:e2304722
3. Xiao Hu#, Wei Xu#, Yilong Ren#, Zhaojie Wang#, Xiaolie He#, Runzhi Huang, Bei Ma, Jingwei Zhao, Rongrong Zhu* and Liming Cheng*. Spinal cord injury: molecular mechanisms and therapeutic interventions. Signal Transduct Target Ther. 2023 Jun 26,8(1):245.
4. Hongxing Hu, Zhaojie Wang, Huiyi Yang, Yuxin Bai, Rongrong Zhu*, Liming Cheng*. Hypoxic Preconditional Engineering Small Extracellular Vesicles Promoted Intervertebral Disc Regeneration by Activating Mir-7-5p/NF-Κb/Cxcl2 Axis. Advanced Science . 2023 Oct 23:e2304722
5. Zheng B, He Y, Yin S, Zhu X, Zhao Q, Yang H, Wang Z*, Zhu R*, Cheng L*. Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury. Research (Wash D C). 2023 May 4,6:0135
6. Chen Li#, Zhourui Wu#, Liqiang Zhou#, Jingliang Shao, Xiao Hu, Wei Xu, Yilong Ren, Xingfei Zhu, Weihong Ge, Kunshan Zhang, Jiping Liu, Runzhi Huang, Jing Yu, Dandan Luo, Xuejiao Yang, Wenmin Zhu, Rongrong Zhu, Changhong Zheng, Yi Eve Sun*, Liming Cheng* , Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury, Signal Transduction and Targeted Therapy, 2022 Mar 2, 7(1):65
7. Rongrong Zhu#, Xingfei Zhu#, Yanjing Zhu, Zhaojie Wang, Xiaolie He,Zhourui Wu, Lei Xue, Wenyong Fang, Ruiqi Huang, Zheng Xu, Xi Qi, Wei Xu, Yan Yu, Yilong Ren, Chen Li, Qian Cheng, Lan Ling, Shilong Wang*, Liming Cheng*, Immunomodulatory Layered Double Hydroxide Nanoparticles Enable Neurogenesis by Targeting Transforming Growth Factor-β Receptor 2, ACS Nano, 2021 Feb 23, 15(2):2812-2830.
8. Yanjing Zhu#, Ruiqi Huang#, Zhourui Wu Z, Simin Song, Liming Cheng*, Rongrong Zhu*. Deep learning-based predictive identification of neural stem cell differentiation. Nature Communication 2021 May 10,12(1):2614
9. Dandan Luo, Weihong Ge*, Xiao Hu, Chen Li, Chiaming Lee, Liqiang Zhou, Zhourui Wu, Juehua Yu, Sheng Lin, Jing Yu, Wei Xu, Lei Chen, Chong Zhang, Kun Jiang, Xingfei Zhu, Haotian Li, Xinpei Gao, Yanan Geng, Bo Jing, Zhen Wang, Changhong Zheng, Rongrong Zhu, Qiao Yan, Quan Lin, Keqiang Ye, Yi E. Sun*, Liming Cheng*, Unbiased transcriptomic analyses reveal distinct effects of immune deficiency in CNS function with and without injury, Protein & Cell, 2019, 10(8) : 566-582.
10. Yanjing Zhu, Ruiqi Huang, Rui Zhu, Wei Xu, Rongrong Zhu*, Liming Cheng*, DeepScreen : An Accurate, Rapid, and Anti-Interference Screening Approach for Nanoformulated Medication by Deep Learning, Advanced Science, 2018, 5(9): 1800909