（1） 多囊卵巢综合征的致病机制 （The pathogenic mechanism of polycystic ovary syndrome） （2） 卵子及胚胎发育的调控机制 （The regulatory mechanism of oocyte and embryo development）
（1） 同济大学医学院学术型硕士生导师（2020.10-至今） Academic Master's Tutor, Tongji University School of Medicine (2020.10-present) （2） 国家自然科学基金项目通讯评审专家（2016.04-至今） NSFC Project Communication Review Expert (2016.04-present) （3） 上海市科技专家库入选专家（2020.06-至今） Shanghai Science and Technology Expert Library Selected Experts (2020.06-present) （4） 上海市医学会生殖医学专科分会青年委员（第三届） Youth Member of the Specialized Branch of Reproductive Medicine of Shanghai Medical Association (3rd Session) （5） 多种SCI期刊的审稿人 Reviewer of a variety of SCI journals
自2008年开始专注于生殖医学方面的基础研究，主要着眼于妇科内分泌疾病——多囊卵巢综合征（PCOS），从mRNA、miRNA、lncRNA和circRNA等不同角度对PCOS激素异常导致卵泡发育障碍的机制进行了全面深入的研究。主持国家自然科学基金项目2项，上海市科委面上项目1项，及其他各级项目累积约10项。研究成果多次在美国生殖医学年会及欧洲生殖医学年会做大会发言，并以第一作者或通讯作者发表SCI论文10篇，申请发明专利1项，实用新型专利1项；多次获得全国妇幼健康科技奖科技成果奖、省级及市级科学技术进步奖。
Since 2008, I have been doing basic research in reproductive medicine, specially focused on gynecological endocrine disease - polycystic ovary syndrome (PCOS). The mechanism of abnormal development of follicles in PCOS patients is investigated at the mRNA, miRNA, lncRNA and circRNA levels. I have presided two NSFC projects, one Shanghai Science and Technology Commission on the surface of the project, and about 10 projects at other levels. The research results have been presented at the Annual Meeting of ASRM and the Annual Meeting of ESHRE. I published 10 SCI papers as a first or correspondent author, applied for one patent for invention and one patent for utility model. And, I have won the National Women's and Children's Health Science and Technology Award for scientific and technological achievements, as well as a number of provincial and municipal science and technology progress awards. 代表性学术论文（Publications, * correspondent author; # first author）：
1）Huang X#*, Wu B#, Chen M#, Hong L, Kong P, Wei Z*, Teng X*. Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome. Aging, 2020, 12(15):15414-15435
2）Chen M#, Huang X#, Liu Y, Lei S, Wu Y, Chen Z, Hong L, Teng X*, Systematic oxidative stress is not associated with live birth rate in young non-obese patients with polycystic ovarian syndrome undergoing assisted reproduction cycles: A prospective cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2020, 253:154–161
3) Chen M#, Wu Y#, Huang X#, Li W, Sun C, Meng Z, Ai A, Hong L, Tang C, Li K, Fu Y, Chen Z, Kong P, Guo Y, Liu W, Ben W, Teng X*. Embryo incubation by time-lapse systems versus conventional incubators in Chinese women with diminished ovarian reserve undergoing IVF/ICSI: a study protocol for a randomised controlled trial. BMJ open. 2020; 10: e038657.
4）Huang X#*, Pan J#, Wu B and Teng X. Construction and analysis of a lncRNA (PWRN2)-mediated ceRNA network reveals the potential roles in oocyte nuclear maturation of PCOS patients. Reproductive Biology and Endocrinology, 2018, 16:73
5）Huang X#*, Liu C#, Hao C, Tang Q, Liu R, Lin S, Zhang L and Yan W. Identification of altered microRNAs and mRNAs in the cumulus cells of PCOS patients: miRNA-509-3p promotes oestradiol secretion by targeting MAP3K8. Reproduction, 2016, 151(6):643-55
6）Huang X#*, Hao C*, Bao H, Wang M and Dai H, Aberrant expression of long noncoding RNAs in cumulus cells isolated from PCOS patients. Journal of Assisted Reproduction and Genetics, 2016, 33(1):111-121
7）Huang X, Hao C*, Shen X, Liu X, Shan Y, Zhang Y, Chen L, Differences in the transcriptional profiles of human cumulus cells isolated from MI and MII oocytes of patients with polycystic ovary syndrome, Reproduction, 2013, 145(6):597-608
8）Huang X, Hao C*, Shen X, Zhang Y and Liu X, RUNX2, GPX3 and PTX3 gene expression profiling in cumulus cells are reflective oocyte/embryo competence and potentially reliable predictors of embryo developmental competence in PCOS patients, Reproductive Biology and Endocrinology, 2013,11:109
