(1) 多囊卵巢综合征的致病机制 (The pathogenic mechanism of polycystic ovary syndrome) (2) 卵子及胚胎发育的调控机制 (The regulatory mechanism of oocyte and embryo development)
自2008年开始专注于生殖医学方面的基础研究,主要着眼于妇科内分泌疾病——多囊卵巢综合征(PCOS),从mRNA、miRNA、lncRNA和circRNA等不同角度对PCOS激素异常导致卵泡发育障碍的机制进行了全面深入的研究。主持国家自然科学基金项目2项,上海市科委面上项目1项,及其他各级项目累积约10项。研究成果多次在美国生殖医学年会及欧洲生殖医学年会做大会发言,并以第一作者或通讯作者发表SCI论文10篇,申请发明专利1项,实用新型专利1项;多次获得全国妇幼健康科技奖科技成果奖、省级及市级科学技术进步奖。
Since 2008, I have been doing basic research in reproductive medicine, specially focused on gynecological endocrine disease - polycystic ovary syndrome (PCOS). The mechanism of abnormal development of follicles in PCOS patients is investigated at the mRNA, miRNA, lncRNA and circRNA levels. I have presided two NSFC projects, one Shanghai Science and Technology Commission on the surface of the project, and about 10 projects at other levels. The research results have been presented at the Annual Meeting of ASRM and the Annual Meeting of ESHRE. I published 10 SCI papers as a first or correspondent author, applied for one patent for invention and one patent for utility model. And, I have won the National Women