主持包括国家自然科学基金在内的各级课题20余项,SCI收录论著40余篇。
课题(近三年):
1. 上海申康医院发展中心:气道管理与呼吸治疗培训基地及规范化培训课程建设,
2. 上海市卫健委:膜孔蛋白Ompk37多拷贝对CRKP耐药影响的机制探讨
3. 上海申康医院发展中心:基于医院信息系统脓毒症快速精准诊断方法的建立与应用的多中心临床研究
4. 上海申康医院发展中心:全生命周期脓毒血症特色专病队列数据库建设
5. 国家自然科学基金:lncRNA GAS5调控自噬在脓毒症性心肌损伤中的作用
文章(近三年):
1. Partially hydrolyzed guar gum attenuates broad-spectrum antibiotic-induced gut microbiota disruption associated with intestinal inflammation and barrier damage in mice. Food Bioscience 2024; 61: 104962. IF 4.8
2. Comparative venom multi-omics reveal the molecular mechanisms driving adaptation to diverse predator-prey ecosystems in closely related sea snakes. Mol Biol Evol 2023; 40(6): msad125. IF 10.8
3. Discovery of an anti-TNF-α 9-mer peptide from a T7 phage display library for the treatment of inflammatory bowel disease. J Medical Chemistry 2023; 66 (10): 6981–6993. IF 8.04
4. Identification of autophagy-related genes and immune cell infiltration characteristics in sepsis via bioinformatic analysis. J Thorac Dis 2023;15(4):1770-1784. IF 3.01
5. Identification of iron metabolism-related genes in the circulation and myocardium of patients with sepsis via applied bioinformatics analysis. Front Cardiovasc Med. 2023, 10: 1018422. IF 5.85
6. Effect of partially hydrolyzed guar gum on the composition and metabolic function of the intestinal flora of healthy mice. Journal of Food Biochemistry, 2022, 46(12):1-15. IF 4.00
7. Study on the mechanism of Fentanyl in pain treatment based on network pharmacology. Journal of Healthcare Engineering 2022; 2022: 4139200. IF 3.82
8. The species identification and genomic analysis of Haemobacillus shengwangii: A novel pathogenic bacterium isolated from a critically ill patient with bloodstream infection. Front Microbiol 2022; 13: 919169. IF 6.06
9. The genomic characterization of KPC-producing klebsiella pneumoniae from the ICU of a teaching hospital in Shanghai, China. Infection and Drug Resistance 2022; 15: 69–81. IF 4.18
10. Two reference-quality sea snake genomes reveal their divergent evolution of adaptive traits and venom systems. Mol Biol Evol 2021; 38 (11): 4867–4883. IF 16.24
11. Profiles of differentially expressed long noncoding RNAs and messenger RNAs in the myocardium of septic mice, Ann Transl Med 2021; 9(3): 199. IF 3.93