【研究方向】
主要研究人诱导多能干细胞（iPSCs）在年龄相关性疾病中的应用与治疗，重点关注眼部年龄相关性黄斑变性（AMD）的干细胞替代治疗。建立人iPSC来源视网膜色素上皮（RPE）细胞的治疗体系，目前进入临床转化阶段。主持上海市卫健委临床研究专项1项和国家自然科学基金项目1项。
My research focuses on the application and therapeutic potential of human induced pluripotent stem cells (iPSCs) in age-related diseases. Currently, our technology using human iPSC-derived retinal pigment epithelial (RPE) cell-based therapeutics for age-related macular degeneration (AMD) has entered the stage of clinical translation. I am currently supported by one Clinical Research Project from the Shanghai Municipal Health Commission and one grant from the National Natural Science Foundation of China.
【近3年通讯/一作发表论文7篇】
（1）Bioinformatics-integrated screening of systemic sclerosis-specific expressed markers to identify therapeutic targets; Frontiers in Immunology; 2023
（2）The increased cfRNA of TNFSF4 in peripheral blood at late gestation and preterm labor: its implication as a noninvasive biomarker for premature delivery; Frontiers in Immunology; 2023
（3）Subconjunctival injection of human umbilical cord mesenchymal stem cells alleviates experimental allergic conjunctivitis via regulating T cell response; Stem Cell Research & Therapy; 2023
（4）Asparagine alleviates naphthalene-induced lens opacity by suppressing ferroptosis; Experimental Eye Research; 2025
（5）miR-143-3p boosts extracellular vesicles to improve the dermal fibrosis of localized scleroderma; Journal of Autoimmunity;2025
（6）PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species; Advanced Science;2025
（7）Naphthalene Metabolites From Long‐Term Environmental Tobacco Smoke Induce the Aging of Retinal Pigment Epithelium; Aging Cell;2025
