作为唯一项目负责人（PI）分别获得美国退伍军人协会研究中心的资助（2012-2024 年，300 万美元）和PSC Partners Seeking a Cure 基金项目的资助（2020-2023 年，6 万美元）；此外，还担任项目负责人或共同负责人获得美国国立卫生研究院（NIH）糖尿病、消化道和肾脏疾病研究分署（NIDDK）和国家防止酒精滥用与酒精中毒研究分署（NIAAA）共计6 项R01 研究基金和2项R21研究基金的资助，资助金额总计达1100 万美元。担任NIH 基金评审委员会及多家国际专业医疗权威机构的评审专家和常驻评审委员。共发表了144 篇研究论文。H 指数（H-index）为59；总SCI 引用达14050 次，近五年内SCI 引用达5768 次。作为主要发明人拥有两项发明专利，其中一项已被加拿大的Griffon Pharma 制药公司买断。
代表性论文:
1) Wan Y, Slevin E, Koyama S, Huang CK, Shetty AK, Li X, Harrison K, Li T, Zhou B, Lorenzo SR, Zhang Y, Salinas JM, Xu W, Klaunig JE, Wu C, Tsukamoto H, Meng F. miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol induced liver injury. Hepatology Communications. 2023 Apr 4;7(4):e0089. doi: 10.1097/HC9.0000000000000089. eCollection 2023 Apr 1. PMID: 37026704
2) Wan Y, Slevin E, Koyama S, Harrison K, Li T, Li X, Zhang Y, Klaunig JE, Wu C, Shetty AK, Huang CK, Meng F. Liver specific deletion of microRNA-34a alleviates ductular reaction and liver fibrosis during experimental cholestasis. FASEB J. 2023 Feb;37(2):e22731. doi: 10.1096/fj.202201453R. PMID: 36583714
3) Slevin E, Koyama S, Harrison K, Wan Y, Klaunig JE, Wu C, Shetty AK, Meng F. Dysbiosis in Gastrointestinal Pathophysiology: Role of the Gut Microbiome in Gulf War Illness. J Cell Mol Med. 2023 Apr;27(7):891-905. doi: 10.1111/jcmm.17631. Epub 2023 Jan 30. PMID: 36716094
4) Wan Y, Li X, Slevin E, Harrison K, Li T, Zhang Y, Klaunig JE, Wu C, Shetty AK, Dong XC, Meng F. Endothelial dysfunction in pathological processes of chronic liver disease during aging. FASEB J. 2022 Jan;36(1):e22125. doi: 10.1096/fj.202101426R. PMID: 34958687
5) Glaser T, Baiocchi L, Zhou T, Francis H, Lenci I, Grassi G, Kennedy L, Liangpunsakul S, Glaser S, Alpini G, Meng F. Pro-inflammatory signalling and gut-liver axis in non-alcoholic and alcoholic steatohepatitis: Differences and similarities along the path. J Cell Mol Med. 2020 Jun;24(11):5955-5965. doi: 10.1111/jcmm.15182. Epub 2020 Apr 21. PMID: 32314869
6) Francis H, Wu N, Alpini G, Meng F. Hepatocyte Autophagy: Maintaining a Toxic-Free Environment. Hepatology. 2020 Aug;72(2):371-374. doi: 10.1002/hep.31219. PMID: 32150757
7) Navas MC, Glaser S, Dhruv H, Celinski S, Alpini G, Meng F. Hepatitis C Virus Infection and Cholangiocarcinoma: An Insight into Epidemiologic Evidences and Hypothetical Mechanisms of Oncogenesis. Am J Pathol. 2019 Jun;189(6):1122-1132. doi: 10.1016/j.ajpath.2019.01.018. Epub 2019 Apr 4. PMID: 30953604
8) McDaniel K, Wu N, Zhou T, Huang L, Sato K, Venter J, Ceci L, Chen D, Ramos-Lorenzo S, Invernizzi P, Bernuzzi F, Wu C, Francis H, Glaser S, Alpini G, Meng F. Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 knockout mice via let-7 microRNA. Hepatology. 2019 Jun;69(6):2562-2578. doi: 10.1002/hep.30542. Epub 2019 Apr 12. PMID: 30723922
9) Wu N, McDaniel K, Zhou T, Ramos-Lorenzo S, Wu C, Huang L, Chen D, Annable T, Francis H, Glaser S, Alpini G, Meng F. Knockout of microRNA-21 attenuates alcoholic hepatitis through VHL/NF-κB signaling pathway in hepatic stellate cells. American journal of physiology. Gastrointestinal and liver physiology. 2018; 315(3):G385-G398. PMID: 29848019.
10) Y Wan, K McDaniel, N Wu, S Ramos-Lorenzo, T Glaser, J Venter, H Francis, L Kennedy, K Sato, T Zhou, T Kyritsi, Q Huang, T Annable, S Glaser, C Wu, G Alpini, and F Meng. Regulation of cellular senescence by miR-34a in alcoholic liver injury. Am J Pathol 187: 2788-2798, 2017.
11) K McDaniel, L Huang, K Sato, N Wu, T Annable, T Zhou, S RamosLorenzo, Y Wan, Q Huang, H Francis, S Glaser, H Tsukamoto, G Alpini, and F Meng. The let-7/lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury. J Biol Chem 292:11336-11347, 2017.
12) Wan Y, Garner J, Wu N, Phillip L, Han Y, McDaniel K, Annable T, Zhou T, Francis H, Glaser S, Huang Q, Alpini G, Meng F. Role of stem cells during diabetic liver injury. J Cell Mol Med. 2016 Feb;20(2):195-203. doi: 10.1111/jcmm.12723. Epub 2015 Dec 9. Review. PMID: 26645107
13) Meng F, Alpini G. Peri-scoping the biliary tree reveals stem cell activation in peribiliary glands in primary sclerosing cholangitis. J Hepatol. 2015 Nov;63(5):1062-3. doi: 10.1016/j.jhep.2015.07.015. Epub 2015 Jul 26. No abstract available. PMID: 26212028
14) Levine P, McDaniel K, Francis H, Kennedy L, Alpini G, Meng F. Molecular mechanisms of stem cell therapy in alcoholic liver disease. Dig Liver Dis. 2014 May;46(5):391-7. doi: 10.1016/j.dld.2013.11.015. Epub 2014 Jan 15. PMID: 24440312
15) McDaniel K, Herrera L, Zhou T, Francis H, Han Y, Levine P, Lin E, Glaser S, Alpini G, Meng F. The functional role of microRNAs in alcoholic liver injury. J Cell Mol Med. 2014 Jan 8. doi: 10.1111/jcmm.12223. [Epub ahead of print] PMID: 24400890
16) Meng F, Francis H, Glaser S, Han Y, Demorrow S, Stokes A, Staloch D, Venter J, White M, Ueno Y, Reid LM, Alpini G. Role of stem cell factor and granulocyte-colony stimulating factor in remodeling during liver regeneration. Hepatology. 2012 Jan;55(1):209-21. PMID: 21932404
17) Meng F, Glaser SS, Francis H, Demorrow S, Han Y, Passarini JD, Stokes A, Cleary JP, Liu X, Venter J, Kumar P, Priester S, Hubble L, Stoloch D, Sharma J, Liu CG, Alpini G. Functional analysis of microRNAs in human hepatocellular cancer stem cells. J Cell Mol Med. 2012 Jan;16(1):160-73. PMID: 21352471
18) Meng F, Alpini G. Confocal laser endomicroscopy in dynamic evaluation of hepatic apoptosis in vivo. Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G762-3. PMID: 21868634
19) Meng F, Han Y, Staloch D, Francis T, Stokes A, Francis H. The H4HR agonist, clobenpropit, suppresses human cholangiocarcinoma progression by disruption of EMT and tumor metastasis. Hepatology. 2011 Nov;54(5):1718-28. PMID: 21793031
20) Alpini G, Glaser SS, Zhang JP, Francis H, Han Y, Gong J, Stokes A, Francis T, Hughart N, Hubble L, Zhuang SM, Meng F. Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer. J Hepatol. 2011 Dec;55(6):1339-45. PMID: 21703189
21) Meng F, Wehbe-Janek H, Henson R, Smith H, Patel T. Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. Oncogene. 2008 Jan 10;27(3):378-86.
22) Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 2007 Aug;133(2):647-58.
23) Meng F, Henson R, Patel T. Chemotherapeutic stress selectively activates NF-kappa B-dependent AKT and VEGF expression in liver cancer-derived endothelial cells. Am J Physiol Cell Physiol. 2007 Aug;293(2):C749-60.
24) Meng F, Henson R, Wehbe H, Patel T. The microRNA let 7A modulates Interleukin-6 dependent Stat-3 survival signaling in malignant human cholangiocytes. J Biol Chem. 2007 Mar 16;282(11):8256-64.
25) Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT, Jiang J, Schmittgen TD, Patel T. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology. 2006 Jun;130(7):2113-29.
26)Meng F, Yamagiwa Y, Ueno Y, Patel T. Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes. J Hepatol. 2006 Jun;44(6):1055-65
