主要从事病原生物学和药学等方面研究,主持国家和省部级科研项目14项,以第一作者或通讯作者在PLoS Pathogens,Advanced Drug Delivery Reviews,Journal of Biological Chemistry,Journal of Proteome Research等国际期刊发表论文40余篇,其中3篇论文被F1000推荐,参编英文专著2部,研究成果多次受邀在国际会议上进行特邀/大会报告交流。相关研究还获得上海明治生命科学奖和上海市科技进步奖等。
近5年主要论文发表(*通讯作者):
1.Ullah H, Qadeer A, Rashid M, Rashid MI, Cheng G*. Recent advances in nucleic acid-based methods for detection of helminth infections and the perspective of biosensors for future development. Parasitology. 2020 Apr;147(4):383-392.
2.Liu J, Zhu L, Wang J, Qiu L, Chen Y, Davis RE, Cheng G*. Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism. PLoS Pathog. 2019 Jun 4;15(6):e1007817.【F1000 Recommended】
3.Giri BR, Mahato RI, Cheng G*. Roles of microRNAs in T cell immunity: Implications for strategy development against infectious diseases. Med Res Rev. 2019 Mar;39(2):706-732.
4.Giri BR, Cheng G*. MicroRNAs, T cell immunity and immunotherapy. Future Medicinal Chemistry. 2019 Aug;11(16):2043-2045.
5.Liu J, Giri BR, Chen Y, Cheng G*. 14-3-3 protein and ubiquitin C acting as SjIAP interaction partners facilitate tegumental integrity in Schistosoma japonicum. Int J Parasitol. 2019 Apr;49(5):355-364.
6.Liu J, Giri BR, Chen Y, Luo R, Xia T, Grevelding CG, Cheng G*. Schistosoma japonicum IAP and Teg20 safeguard tegumental integrity by inhibiting cellular apoptosis. PLoS Negl Trop Dis. 2018 Jul 25;12(7):e0006654.
7.Wang L, Giri BR, Chen Y, Xia T, Liu J, Li H, Li J, Cheng G*. Molecular characterization, expression profile, and preliminary evaluation of diagnostic potential of CD63 in Schistosoma japonicum. Parasitol Res. 2018 Nov;117(11):3625-3631.
8.Giri BR, Li H, Chen Y, Cheng G*. Preliminary evaluation of neoblast-like stem cell factor and transcript expression profiles in Schistosoma japonicum. Acta Trop. 2018 Nov;187:57-64.
9.Liu J, Zhu L, Wang L, Chen Y, Giri BR, Li J, Cheng G*. Isolation and Characterization of Extracellular Vesicles from Adult Schistosoma japonicum. J Vis Exp. 2018 May 22;(135). doi: 10.3791/57514.
10.Giri BR, Ye J, Chen Y, Wei C*, Cheng G*. In silico analysis of endogenous siRNAs associated transposable elements and NATs in Schistosoma japonicum reveals their putative roles during reproductive development. Parasitol Res. 2018 May;117(5):1549-1558.
11.Giri BR, Du X, Xia T, Chen Y, Li H, Cheng G*. Molecular characterization and expression profile of nanos in Schistosoma japonicum and its influence on the expression several mammalian stem cell factors. Parasitol Res. 2017 Jul;116(7):1947-1954.
12.Zhu L, Zhao J, Wang J, Hu C, Peng J, Luo R, Zhou C, Liu J, Lin J, Jin Y, Davis RE*, Cheng G*. MicroRNAs Are Involved in the Regulation of Ovary Development in the Pathogenic Blood Fluke Schistosoma japonicum. PLoS Pathog. 2016 Feb 12;12(2):e1005423.【F1000 Recommended】
13.Cheng G*. Circulating miRNAs: Roles in cancer diagnosis, prognosis and therapy. Adv Drug Deliv Rev. 2015 Jan;81:75-93.
14.Zhu L, Dao J, Du X, Li H, Lu K, Liu J, Cheng G*. Altered levels of circulating miRNAs are associated Schistosoma japonicum infection in mice. Parasit Vectors. 2015 Apr 1;8:196.