代表性论文
1. Jiawen, Zhang#; Yunfei, Chen#; Xianfei, Chen; Wen, Zhang; Linlin, Zhao; Linjun, Weng; Hongling, Tian; Zhiqiang, Wu; Xiao, Tan; Xin, Ge; Ping, Wang*; Lan, Fang*; Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer, Cell Death and Differentiation, 2020, 28(28): 139-155.
2. Chen, Xianfei; Chen, Yunfei*; Ubiquitination of cGAS by TRAF6 regulates anti-DNA viral innate immune responses. , Biochem Biophys Res Commun, 2019, 514(3): 659-664.
3. Chen, Yunfei#; Wang, Lufan#; Jin, Jiali; Luan, Yi; Chen, Cong; Li, Yu; Chu, Hongshang; Wang, Xinbo; Liao, Guanghong; Yu, Yue; Teng, Hongqi; Wang, Yanming; Pan, Weijuan; Fang, Lan; Liao, Lujian; Jiang, Zhengfan; Ge, Xin; Li, Bin; Wang, Ping*; p38 inhibition provides anti-DNA virus immunity by regulation of USP21 phosphorylation and STING activation, JOURNAL OF EXPERIMENTAL MEDICINE, 2017, 214(4): 991-1010.
4. Li, H.#; Xiao, N.#; Wang, Y.#; Wang, R.#; Chen, Y.; Pan, W.; Liu, D.; Li, S.; Sun, J.; Zhang, K.; Sun, Y.; Ge, X.*; Smurf1 regulates lung cancer cell growth and migration through interaction with and ubiquitination of PIPKI gamma, ONCOGENE, 2017,36(41): 5668-5680.
5. Yunfei Chen#; Lufan Wang#; Xiaomu Cheng; Xin Ge; Ping Wang*; An ultrasensitive system for measuring the USPs and OTULIN activity using Nanoluc as a reporter , Biochemical and Biophysical Research Communications, 2014, 455(3–4): 178-183. 专利:
1.陈云飞; 王路凡; 程晓牧; 王平, Ub-Nanoluc、Ub-Ub-GS-Nanoluc报告基因系统及其构建和应用, 2018.2.23-2038.2.23, 中国, ZL201410053262.4 专利第一发明人。项目主持:
1.USP21 参与调控 I 型干扰素信号通路机制和功能的研究,主持,2016/01-2018/12,国家自然科学基金青年科学基金项目, 31501135, 22 万元,结题
2.去线性泛素化酶OTULIN抑制细胞感应DNA信号调控肿瘤微环境的研究,主持,2020/01-2023/02国家自然科学基金面上项目 项目批准号:81972676 60万元,在研
3.SirT3通过cGAS-STING信号通路调控抗DNA病原物天然免疫反应功能及机制的研究,主持, 2019/07-2022/06上海市自然科学基金面上项目 项目编号 19ZR1439400 22 万元,在研