主持国家自然科学基金青年科学基金项目和上海市科委“科技创新行动计划”项目各一项,作为项目骨干参与两项国家重点研发计划。近5年以第一作者(含共同)或共同通讯作者发表SCI论文6篇,影响因子总计超过40分。申请国家发明专利一项。获得2021 STEM CELLS Young Investigator Award。
代表性文章:
1. Ma, L., Du, Y., Hui, Y., Li, N., Fan, B., Zhang, XJ., Li, X., Hong, W., Wu, Z., Zhang, S., Zhou, S., Xu, X., Zhou, Z., Jiang, C., Liu, L., Zhang, X. Developmental programming and lineage branching of early human telencephalon. The EMBO Journal, 2021 Sep 24; e107277. doi: 10.15252/embj.2020107277.
2. Ma, L., Du, Y., Xu, X., Feng, H., Hui, Y., Li, N., Jiang, G., Zhang, X., Li, X., Liu, L. β-catenin deletion in regional neural progenitors leads to congenital hydrocephalus in mice. Neuroscience Bulletin, 2021 Aug 30. doi: 10.1007/s12264-021-00763-z.
3. Xu, X.*, Du, Y.*, Ma, L.*, Zhang, S., Shi, L., Chen, Z., Zhou, Z., Hui, Y., Liu, Y., Fang, Y., Fan, B., Liu, Z., Li, N., Zhou, S., Jianf, C., Liu, L., Zhang, X. Mapping germ-layer specification preventing genes in hPSCs via genome-scale CRISPR screening. iScience, 2021, 24, 101926.
4. Shi, L., Li, W., Liu, Y., Chen, Z., Hui, Y., Hao, P., Xu, X., Zhang, S., Feng, H., Zhang, B., Zhou, S., Li, N., Xiao, L., Liu, L., Ma, L.#, Zhang, X.# Generation of hypoimmunogenic human pluripotent stem cells via expression of membrane-bound and secreted β2m-HLA-G fusion proteins. Stem Cells, 2020, 38, 1423-1437.
5. Ma, L., Wang, Y., Hui, Y., Du, Y., Chen, Z., Feng, H., Zhang, S., Li, N., Song, J., Fang, Y., Xu, X., Shi, L., Zhang, B., Cheng, J., Zhou, S., Liu, L., Zhang, X. WNT/NOTCH Pathway Is Essential for the Maintenance and Expansion of Human MGE Progenitors. Stem Cell Reports, 2019, 12, 934-949. IF:7.765
6. Wang, Y.*, Xu, C.*, Ma, L.*, Mou, Y., Zhang, B., Zhou, S., Tian, Y., Trinh, J., Zhang, X., and Li, X.J. Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology. Life Science Alliance, 2019, 2.