博士毕业于美国内布拉斯加大学医学中心并留校从事博士后研究，2018年加入同济大学医学院。
入选全国“青马工程”首期科技人才，上海市科技英才。长期致力于神经退行性疾病的发病机制与再生修复方面的研究，重点研究干细胞及其外泌体在神经退行性疾病治疗中的应用前景与作用机制。
近五年以第一作者或通讯作者（含共同）身份在Am J Resp Crit Care、Signal Transduct Target Ther（2篇）、Aging Res Rev、Nano Lett等国际一流学术期刊发表研究论著40余篇。
主持国家自然科学基金3项（面上项目2项，青年基金1项）等7项国家级/省部级科研课题。
部分代表性研究论文包括：
1. Gao Gǂ, Li Cǂ, Ma Yǂ, Liang Zǂ, Li Y, Li X, Fu S, Wang Y*, Xia X*, Zheng JC*. Neural stem cell-derived extracellular vesicles mitigate Alzheimer disease-like phenotypes in a preclinical mouse model. Signal Transduct Target Ther. 2023; 8(1):228.
2. Yuan Pǂ, Bi Yǂ, Luo Yǂ, Tao Q, Gong S, Wang Y, Xiong L*, Xia X*, Zheng JC*. Cognitive dysfunction of patients infected with SARS-CoV-2 omicron variant in Shanghai, China. Transl Neurodegener. 2023; 12(1):28.
3. Fu Sǂ, Li Cǂ, Yang W, Chen H, Wang Y, Zhu Y, Zhu J, Zhang B*, Xia X*, Zheng JC*. Insulin-incubated palladium clusters alleviate Alzheimer disease-like phenotypes in a preclinical mouse model. Medcomm. 2023; 4(4):e272.
4. Xia Xǂ*, Wang Yǂ, Zheng JC*. Internal m7G methylation: a novel epitranscriptomic contributor in brain development and diseases. Mol Ther-Nucl Acids. 2023; 31:295-308.
5. Yuan Pǂ, Li Jǂ, Liu J, Liu H, Gong S, Wang L, Liu J, Li C, Wang Y, Xia X*, Zheng JC*. Cognitive dysfunction in patients with pulmonary hypertension. Am J Resp Crit Care. 2022; 206(10):1289-1293.
6. Fu Sǂ, Chen Hǂ, Yang W, Xia X*, Zhao S, Xu X, Ai P, Cai Q, Li X, Wang Y, Zhu J, Zhang B*, Zheng JC*.ROS-targeted depression therapy via BSA-incubated ceria nanocluster. Nano Letters. 2022; 22(11):4519-4527.
7. Xia X, Wang Y, Qin Y, Zhao S, Zheng JC*. Exosome: a novel neurotransmission modulator or non-canonical neurotransmitter. Ageing Res Rev. 2022; 74:101558.
8. Li Yǂ, Xia Xǂ*, Wang Y, Zheng JC*. Mitochondrial Dysfunction in Microglia: A Novel Perspective for Pathogenesis of Alzheimer Disease. J Neuroinflamm. 2022; 19(1):248.
9. Fu Sǂ, Chen Hǂ, Zhao Sǂ, Yang W, Xia X*, Xu, X, Liang Z, Feng X, Wang Z, Ai P, Ding L, Cai Q, Wang Y, Zhang Y, Zhu J, Zhang B*, Zheng JC*. Insulin-incubated palladium clusters promote recovery after brain injury. J Nanobiotechnol. 2022; 20:299.
10. Gao Gǂ, Li Cǂ, Zhu Jǂ, Sheng S, Liang Z, Fu S, Li X, Sun Y, Wang Y, Feng X, Xia X*, Zheng JC*. Induced neural stem/progenitor cell-derived extracellular vesicles promote recovery post stroke. Clin Transl Med. 2022; 12(6):e936.
11. Ding Lǂ, Xu Xǂ, Li Cǂ, Wang Y*, Xia X*, Zheng JC*. Glutaminase in microglia: a novel regulator of neuroinflammation. Brain Behav Immun. 2021; 92:139-156.
12. Xia Xǂ*, Wang Yǂ, Zheng JC*. COVID-19 and Alzheimer's disease: how one crisis worsens the other. Transl Neurodegener. 2021; 10(1):15.
13. Xia Xǂ, Li Cǂ, Wang Y, Deng X, Ma Y, Ding L, Zheng JC*. Reprogrammed astrocytes display higher neurogenic competence, migration ability and cell death resistance than reprogrammed fibroblasts. Transl. Neurodegener.2020; 9:6
14. Xia X, Wang Y, Huang Y, Zhang H, Lu H, Zheng JC*. Exosomal MiRNAs in Central Nervous System Diseases: Biomarkers, Pathological Mediators, Protective Factors and Therapeutic Agents. Prog Neurobiol.2019; 183:101694
15. Ma Kǂ, Deng Xǂ, Xia Xǂ, Fan Z, Qi X, Wang Y, Li Y, Ma Y, Chen Q, Peng H, Ding J, Li C, Huang Y*, Tian C*, Zheng JC*. Direct Conversion of Mouse Astrocytes into Neural Progenitor Cells and Specific Lineages of Neurons. Transl. Neurodegener. 2018; 5(7):29
