课题/FUNDING:
1.国家自然科学基金委员会,青年项目,81500052,不同结局结节病血清学标记物动态变化及免疫机制研究,2016-01至2018-12,21万,结题,主持。
2. 上海市卫生健康委员会,卫生行业临床研究专项青年项目,20204Y0383,特发性肺纤维化综合评分系统的建立与验证,2021-01至2023-12,5万,在研,主持。
3. 国家自然科学基金委员会,重点项目,81730002,特发性肺纤维化急性加重肺损伤免疫调控机制及干预研究,2018-01至2022-12,293万,在研,参加。
发表文章/PUBLICATIONS:
第一作者或通讯作者(第一或通讯,*通讯作者,#同等贡献)
Liu J, Jia J, Wang S, Zhang J, Xian S, Zheng Z, Deng L, Feng Y*, Zhang Y*, Zhang J*. Prognostic Ability of Enhancer RNAs in Metastasis of Non-Small Cell Lung Cancer. Molecules. 2022 Jun 26;27(13):4108.
Zhang Y#, Du SS#, Zhao MM#, Li QH#, Zhou Y, Song JC, Chen T, Shi JY, Jie B, Li W, Shen L, Zhang F, Su YL, Hu Y, Lower EE, Baughman RP, Li H. Chest high-resolution computed tomography can make higher accurate stages for thoracic sarcoidosis than X-ray. BMC Pulm Med. 2022 Apr 16;22(1):146.
Wu X#, Yin C#, Chen X#, Zhang Y#, Su Y, Shi J, Weng D, Jiang X, Zhang A, Zhang W, Li H. Idiopathic Pulmonary Fibrosis Mortality Risk Prediction Based on Artificial Intelligence: The CTPF Model. Front Pharmacol. 2022 Apr 26;13:878764.
Shen M#, Zhou Y#, Gu W, Yin C, Wang Y*, Zhang Y*. Application of neck ultrasound in the diagnosis of sarcoidosis. BMC Pulm Med. 2021 Dec 15;21(1):412.
Chen X#, Zhang Y#, Xu J, Li H. Establishment and validation of a predictive model for nontuberculous mycobacterial infections in acid-fast bacilli smear-positive patients. Clin Respir J. 2021 Jul 15.
Shen L#, Zhang Y#, Su Y, Weng D, Zhang F, Wu Q, Chen T, Li Q, Zhou Y, Hu Y, Jiang X, Jin X, Zhang A, Li H. New pulmonary rehabilitation exercise for pulmonary fibrosis to improve the pulmonary function and quality of life of patients with idiopathic pulmonary fibrosis: a randomized control trial. Ann Palliat Med. 2021 Jul;10(7):7289-7297.
Chen T#, Li QH#, Zhang Y#, Yin CS, Weng D, Zhou Y, Hu Y, Shi JY, Chen YN, Ye S, Wang XD, Wu CY, Huang Y, Zhang AH, Li HP. The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features. Clin Exp Rheumatol. 2021 Mar 30.
Zhang Y#, Li N#, Li Q#, Zhou Y#, Zhang F, Chen T, Shen L, Su Y, Hu Y, Li H* . Analysis of the clinical characteristics of 176 patients with pathologically confirmed cryptogenic organizing pneumonia. Ann Transl Med 2020;8(12):763.
Zhou Y# , Zhang Y# , Zhao M# , Li Q# , Li H*. sIL-2R levels predict the spontaneous remission in sarcoidosis. Respir Med. 2020 Sep;171:106115.
Zhao M#, Song J#, Du S#, Zhang Y#, Zhou Y, Li Q, Weng D*, Li H*. Serum IL-35 levels are Associated with Activity and Progression of Sarcoidosis. Front. Immunol. 2020 May 19;11:977.
Weng D#, Chen X#, Qiu H#, Zhang Y# , Li Q, Zhao M, Wu Q, Chen T, Hu Y, Wang L, Wei Y, Du Y, Chen S, Zhou Y, Zhang F, Shen L, Su Y, Kolb M, Li H*. The role of infection in acute exacerbation of Idiopathic Pulmonary Fibrosis. Mediators Inflamm. 2019 Jan 3;2019:5160694.
Li QH#, Zhang Y#, Zhao MM#, Gu Y#, Hu Y, Su YL, Zhang F, Shen L, Zhou Y, Li HP*. Simultaneous amplification and testing method for Mycobacterium tuberculosis rRNA to differentiate sputum-negative tuberculosis from sarcoidosis. Am J Physiol Lung Cell Mol Physiol. 2019, 1;316(3):L519-L524.
Zhang Y, Zhang SX, Trivedi J, et al. Pleural fluid secondary to pulmonary cryptococcal infection: a case report and review of the literature. BMC Infect Dis. 2019;19(1):710.
Yang J#, Zhang Y#, Sun X#, Gusdon AM, Song N, Chen L, Jiang G* , Huang Y* . The prognostic value of multiorgan metastases in patients with non-small cell lung cancer and its variants: a SEER-based study. J Cancer Res Clin Oncol. 2018 Jul 12.
Li N#, Weng D#, Wang SM#, Zhang Y#, Chen SS, Yin ZF, Zhai J, Scoble J, Williams CC, Chen T, Qiu H, Wu Q, Zhao MM, Lu LQ, Mulet X, Li HP*. Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury. Drug Deliv. 2017 Nov;24(1):17701781.
Zhang X#, Kuang Y#, Zhang Y#, He K, Lechtzin N, Zeng M, Yung RC, Xie C*. Shifted focus of bronchoalveolar lavage in patients with suspected thoracic malignancy: an analysis of 224 patients. J Thorac Dis. 2016 Nov;8(11):32453254.
Zhang Y#, Li N# , Zhang Y# , Li H* , Chen X, Wang S, Zhang X, Zhang R, Xu J, Shi J, Yung RC. Clinical analysis of 76 patients pathologically diagnosed with pulmonary cryptococcosis. Eur Respir J. 2012 Nov;40(5):1191-200.
Zhang Y#, Chen X#, Hu Y#, Du S#, Shen L, He Y, Zhang Y, Zhang X, Li H*, Yung RC. Preliminary characterizations of a serum biomarker for sarcoidosis by comparative proteomic approach with tandem-mass spectrometry in ethnic Han Chinese patients. Respir Res. 2013 Feb 11;14(1):18.
Zhang Y#, Wang KP*. Evolution of transbronchial needle aspiration - a hybrid method. J Thorac Dis. 2013 Jun;5(3):234-9.
Hallowell RW, Collins SL, Craig JM, Zhang Y, et al. mTORC2 signalling regulates M2 macrophage differentiation and response to helminth infection and adaptive thermogenesis. Nature Communications. 2017 Jan 27;8:14208.