2017年入选上海市人才发展计划。2019年获得上海交通大学医学院双百人计划“研究型医师”项目。2012、2016、2021年获得国家自然基金项目资助。目前已在国内外发表第一作者或通讯作者论文30余篇(SCI论文20篇)。2012年以高级访问学者赴加拿大多伦多大学进修,师从胰岛功能领域国际知名学者Michael Wheeler教授。
Selected for the Shanghai Talent Development Plan in 2017. In 2019, awarded the "Research Physician" project under the Double Hundred Talents Program of Shanghai Jiao Tong University School of Medicine. Received funding from the National Natural Science Foundation of China in 2012, 2016, and 2021. Currently, over 30 first author or corresponding author papers (20 SCI papers) have been published both domestically and internationally. In 2012, he went to the University of Toronto in Canada as a senior visiting scholar to study under internationally renowned scholar in the field of pancreatic islet function, Professor Michael Wheeler.
科研项目
Extramural Grants/Award Amount (As Principal Investigator):
1. 国家自然科学基金面上项目,82170867,《自噬核心蛋白ATG101介导的自噬对脂肪组织能量稳态的调控作用及其机制研究》2022/01-2025/12,55万,在研,主持
2. 上海市‘科技创新行动计划’生物医药领域科技支撑项目,20S31903200,《针对特殊类型糖尿病相关基因的分子诊断试剂盒开发》,2020/10-2023/09,35万,在研,主持
3. 国家自然科学基金面上项目,81670791,《GLP-1R结合蛋白SERP1抑制内质网应激所致肝脏脂质沉积的作用及机制》2017/01–2020/12,58万,已结题,主持
4.国家自然青年科学基金,81200564,《GNAS1低甲基化在胰岛细胞瘤增殖失控中作用的研究》2013/01–2015/12,25万,已结题,主持
5. 上海交通大学医学院双百人计划“研究型医师”项目,20191920,《评价唑来磷酸注射液治疗代谢手术后并发骨质疏松症的有效性和安全性研究》2019/10-2022/09,100万,在研,主持
6. 上海市人才发展资金资助计划,《胰岛素样生长因子2(IGF2)在胰岛素瘤细胞增殖失控中的作用研究》2017/05–2020/01,20万,已结题,主持
文章发表
Publications (*Corresponding author, #Co-first Author)
1. Shaobo Li, Pin Zhang, Jianzhong Di, Xiaodong Han, Yinfang Tu, Di Yang, Rongrong Xu, Yunfeng Xiao, Jian Zhou, Yuqian Bao, Jun Yin, Haoyong Yu*, Weiping Jia*, Junfeng Han*. Associations of change in body fat percentage with baseline body composition and diabetes remission after bariatric surgery. Obesity (Silver Spring). 2024 May;32(5):871-887.doi: 10.1002/oby.24003.
2. Xuejuan Zhu, Xinran Wang, Jingang Wang, Lei Du, Zhen-Ning Zhang, Donglei Zhou*, Junfeng Han*, Bing Luan*. Intermittent Fasting-Induced Orm2 Promotes Adipose Browning via the GP130/IL23R-p38 Cascade. Adv Sci (Weinh). 2024 Sep 9:e2407789.doi: 10.1002/advs.202407789.
3. Di Yang, Rongrong Xu, Yinfang Tu, Yunfeng Xiao, Hongwei Zhang, Weijie Liu, Pin Zhang, Haoyong Yu, Yuqian Bao, Ying Yang*, Junfeng Han*. Effect of regional body composition changes on bone density remodeling after sleeve gastrectomy. Front Endocrinol (Lausanne). 2023 Sep 11:14:1238060.doi: 10.3389/fendo.2023.1238060.
4. Liu H, Yang D, Li S, Xiao Y, Tu Y, Peng D, Bao Y, Han J*, Yu H*. A Reliable Estimate of Visceral Fat Area From Simple Anthropometric Measurements in Chinese Overweight and Obese Individuals.Front Endocrinol (Lausanne). 2022 Jun 23:13:916124. doi: 10.3389/fendo.2022.916124.
5. Yang D, Ye Y, Tu Y, Xu R, Xiao Y, Zhang H, Liu W, Zhang P, Yu H, Bao Y, Han J*. Sex-specific differences in bone mineral density loss after sleeve gastrectomy. Front Med (Lausanne). 2022 Oct 26;9:957478. doi: 10.3389/fmed.2022.957478. eCollection 2022. (IF 5.058)
6. Bai N, Lu X, Jin L, Alimujiang M, Ma J, Hu F, Xu Y, Sun J, Xu J, Zhang R, Han J*, Hu C*, Yang Y*. CLSTN3 gene variant associates with obesity risk and contributes to dysfunction in white adipose tissue. Mol Metab. 2022 Sep;63:101531.doi: 10.1016/j.molmet.2022.101531. (共同通讯作者)(IF 8.568)
7. Shaobo Li, Haoyong Yu, Pin Zhang, Yinfang Tu, Yunfeng Xiao, Di Yang, Yuqian Bao, Junfeng Han*, Weiping Jia*. The Nonlinear Relationship Between Psoas Cross-sectional Area and BMI: A New Observation and Its Insights Into Diabetes Remission After Roux-en-Y Gastric Bypass. Diabetes Care. 2021 Dec;44(12):2783-2786.doi: 10.2337/dc20-2907. (共同通讯作者)(IF 19.112)
8. Suzhen Chen*, Xiaoxiao Liu, Chao Peng, Chang Tan, Honglin Sun, He Liu, Yao Zhang, Ping Wu, Can Cui, Chuchu Liu, Di Yang, Zhiqiang Li, Junxi Lu, Jian Guan, Xisong Ke, Renxiao Wang, Xiaohai Bo, Xiaojun Xu*, Junfeng Han*, Junli Liu*.The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity. Cell Metab. 2021 Mar 2;33(3):565-580.e7.doi: 10.1016/j.cmet.2021.02.007. (共同通讯作者)(IF 21.567)
9. Ma J, Huang X, Zhao J, Lu J, Lu W, Bao Y, Zhou J*, Han J*. CGM for insulinoma screening: a prospective and observational case-control study. Endocr Relat Cancer. 2021 May;28(5):291-300. doi: 10.1530/ERC-20-0447. (共同通讯作者)(IF 4.8)
10. Li S, Lu J, Gu G, Bai W, Ye Y, Bao Y, Yu H*, Han J*. Serum Creatinine-to-Cystatin C Ratio in the Progression Monitoring of Non-alcoholic Fatty Liver Disease. Front Physiol. 2021 Apr 7;12:664100. doi: 10.3389/fphys.2021.664100. eCollection 2021. (共同通讯作者)(IF 3.367)
11. Wang J, Ma J, Yu H, Zhang P, Han J*, Bao Y. Unacylated ghrelin is correlated with the decline of bone mineral density after Roux-en-Y gastric bypass in obese Chinese with type 2 diabetes. Surg Obes Relat Dis. 2019 Sep;15(9):1473-1480. doi: 10.1016/j.soard.2019.04.011. (IF=4.496)
12. Chen SQ, Niu Q, Ju LP, Alimujiang M, Yan H, Bai NN, Xu J, Fang QC, Han JF*, Yang Y*, Jia WP. Predicted secreted protein analysis reveals synaptogenic function of Clstn3 during WAT browning and BAT activation in mice. Acta Pharmacol Sin. 2019, 40(8):999-1009. (共同通讯作者)(IF 5.064)