主持项目:
国家自然科学基金委员会,面上项目,82473638,大气NPs共污染致胎-婴小脑铁代谢失稳态预测发育性协调障碍成年期发展,2025-01至2028-12
国家自然科学基金委员会面上项目,81673179,DNA甲基化动态修饰介导的“早期儿”认知-运动障碍预警评估模式研究,2017/01-2020/12
国家自然科学基金委员会青年项目,81402687,孕期PM2.5自然暴露模式对子代认知-运动发育的影响及表观修饰机制研究,2015/01-2017/12
上海市科学技术委员会,技术标准类课题,21DZ2202000,儿童发育性协调障碍早期筛查及整合运动干预标准化模式建设,2021-10至2024-9, 15万
主持上海市科学技术委员会动物实验课题,19140903100,孕鼠PM2.5“自然暴露”致甲状腺素表观调控通路失稳态及介导子代神经行为障碍模型研究,2019/05-2022/04,在研
上海市科学技术委员会重点课题(长三角联合攻关项目),15495810500,名称:长三角“智慧保健”-婴幼儿智护体系建设关键筛查技术研究及示范应用,2015/06-2017/06,结题,主持
上海市科学技术委员会引导类项目,14411970900,名称:高危儿发育性运动协调障碍预警评估及生态干预模式研究,2014/08-2017/09
上海市科学技术委员会动物实验课题,18140903100,PM2.5浓缩仓暴露致不育症小鼠及不同“减”污染模式下表观跨代遗传模型,2018/05-2021/04
上海市卫生健康委老龄化和妇儿健康研究专项2020YJZX0213,孤独症合并运动协调障碍“动力系统”超早期干预模式研究,2020/08-2023/07
浦东新区卫生健康委员会联合攻关项目,围孕期亚临床型甲状腺疾病致子代发育性协调障碍“妇幼整 链式”预警评估模式建设, 2020/07-2023/06
上海市申康医院发展中心适宜技术联合开发推广应用项目(子课题),SHDC12016239,早期儿发育性运动协调障碍三阶“级-联”筛查模式研究及临床应用,2016/11-2019/11
上海市公共卫生三年行动计划重点学科人才项目,15GWZK0401子课题,儿童认知-运动发育早期评估模式研究,2015/01-2018/12 主持浦东新区卫生局卫生(计生)科技项目,PW2013-D9、孕产期PM2.5相关疾病预警预报技术和应用效果研究、2013/07-2016/07
上海市营养学会课题,SHYY2018102,守护母爱计划-中国城市人口孕婴多阶段纯母乳喂养支持系统相关因素研究,2018/09-2020/12、103.5万
Study on Early Childhood Cognitive-motor Early Warning Evaluation Model Mediated by Dynamic Modification of DNA Methylation (granted by the National Natural Science Foundation of China), 81673179,2017/01-2020/12
Effects of PM2.5 natural exposure during pregnancy on infants' cognitive-motor development and the mechanism of epigenetic modification (granted by the National Natural Science Foundation of China), 81402687,2017/01-2020/12
Study on the model of thyroxine regulatory pathway Induced by PM2.5 "Natural Exposure" in Pregnant Rats and Mediating the Neurobehavioral Disorder of Offspring (granted by Shanghai Science and Technology Committee), 19140903100,2019/05-2022/04
"Wisdom health care" in the Yangtze River Delta-key screening technology research and demonstration application of infant mobile health care system (granted by Shanghai Science and Technology Committee), 15495810500,2015/06-2017/06
Early warning assessment and ecological intervention model of developmental coordination disorder in high risk infants (granted by Shanghai Science and Technology Committee), 14411970900,2014/08-2017/09
"Dynamic System" based early intervention model of Autism and Motor Coordination Disorder (granted by Shanghai Municipal Health Commission’s Special Project on Aging and Women’s and Children’s Health) 2020YJZX0213, 2020/08-2023/07
Effects of PM2.5 concentrated exposure on infertility mouse and model of transgenerational epigenetics under the condition of ‘decreasing’ pollution (granted by Shanghai Science and Technology Committee), 2019/05-2022/04
Perinatal subclinical thyroid disease causes offspring developmental coordination disorder: constructing a "maternal and child integrated chain" early warning assessment model (granted by joint research project of Pudong Health Commission), 15495810500,2020/07-2023/06,
Research and clinical application of the third-order "cascade" screening model for developmental motor coordination disorder during early childhood (granted by Shanghai Shenkang Hospital Development Center) SHDC12016239, 2016/11-2019/11
Study on early assessment model of children's cognitive-motor development (supported by Talent Project of Shanghai Public Health Three-year Action Plan Key Discipline, sub-project), 15GWZK0401, 2015/01-2018/12
Early warning and forecasting technology and effective research of PM2.5 related diseases during pregnancy and childbirth (granted by joint research project of Pudong Health Commission), PW2013-D9, 2013/07-2016/07, completed.
Protecting mother’s loving for children: research on related factors of multi-stage exclusive breastfeeding support system for Chinese urban population (granted by Shanghai Nutrition Society Project), SHYY2018102, 2018/09-2020/12
第一作者或通讯作者身份发表论文
Papers in recent years have been published in English Journal
Cai J, Shen Y, Meng X, Zhao Y, Niu Y, Chen R, Du W, Quan G, Barnett AL, Jones G, Kan H, Hua J*. Association of developmental coordination disorder with early-life exposure to fine particulate matter in Chinese preschoolers. Innovation (Camb). 2022 Nov 4;4(1):100347. eCollection 2023 Jan 30. doi: 32.10.1016/j.xinn.2022.100347. PMID: 36425095; PMCID: PMC9678769. 32.1
Geng Shanshan, Wang Weijie, Huang Liping, Xie Jinhong, Williams Gareth J., Baker Charlie, Du Wenchong, Hua Jing. Association between screen time and suspected Developmental Coordination Disorder in preschoolers: a national population-based study in China. Front. Public Health 27 March 2023. 11:1152321 DOI: 10.3389/fpubh.2023.1152321
You H, Shi J, Huang F, Wei Z, Jones G, Du W, Hua J. Advances in Genetics and Epigenetics of Developmental Coordination Disorder in Children. Brain Sci. 2023 Jun 11;13(6):940. doi: 10.3390/brainsci13060940. PMID: 37371418; PMCID: PMC10296699.
Lyu J, Groeger JA, Barnett AL, Li H, Wang L, Zhang J, Du W, Hua J*. Associations between gestational age and childhood sleep: a national retrospective cohort study. BMC Med. 2022 Aug 8;20(1):253. doi: 10.1186/s12916-022-02443-9. PMID: 35934710; PMCID: PMC9358861
Jiang H, Guo J, Li J, Li C, Du W, Canavese F, Baker C, Ying H, Hua J. Artificial Neural Network Modeling to Predict Neonatal Metabolic Bone Disease in the Prenatal and Postnatal Periods. JAMA Netw Open. 2023 Jan 3;6(1):e2251849. doi: 10.1001/jamanetworkopen.2022.51849. PMID: 36689226.Format: IF 13.353
Yang Y, Yang T, Zhou J, Cao Z, Liao Z, Zhao Y, Su X, He J, Hua J*. Prenatal exposure to concentrated ambient PM2.5 results in spatial memory defects regulated by DNA methylation in male mice offspring. Environ Sci Pollut Res Int. 2023 Mar;30(12):35142-35152. doi: 10.1007/s11356-022-24663-5. Epub 2022 Dec 17. PMID: 36526934; PMCID: PMC10017658. Format:. IF 5.190
Cai J, Shen Y, Zhao Y, Meng X, Niu Y, Chen R, Quan G, Li H, Groeger JA, Du W, Hua J*, Kan H. Early Life Exposure to PM2.5 and Sleep Disturbances in Preschoolers from 551 Cities of China. Am J Respir Crit Care Med. 2022 Sep 28. doi: 10.1164/rccm.202204-0740OC. Epub ahead of print. PMID: 36170612. IF 30.528
Hua J*, Xie J, Baker C, Du W. National Prevalence of Excessive Screen Exposure Among Chinese Preschoolers. JAMA Netw Open. 2022 Jul 1;5(7):e2224244. doi: 10.1001/jamanetworkopen.2022.24244. PMID: 35900767.
Jing Hua*, Gareth J. Williams, Anna L. Barnett, Jiajia Zhang, Hua Jin, Manyun Xu, Juan Chen, Yingchun Zhou, Guixiong Gu, Wenchong Du. Association of the onset of self-feeding with subsequent suspected Developmental Coordination Disorder: a prospective cohort study in China. Front Psychiatry 2022, 06 May 2022 doi: 10.3389/fpsyt.2022.818771
Jing Hua*, Anna L. Barnett, Yao Lin, Hongyan Guan, Yuanjie Sun, Gareth J. Williams, Yuxuan Fu, Yingchun Zhou, Wenchong Du Association of Gestational Age at Birth with Subsequent Neurodevelopment in Early Childhood: a national retrospective cohort study in China. Front Pediatrics 2022, DOI: 10.3389/fped.2022.860192
Hua J*, Williams GJ, Jin H, Chen J, Xu M, Zhou Y, Gu G, Du W: Early Motor Milestones in Infancy and Later Motor Impairments: A Population-Based Data Linkage Study. Front Psychiatry 2022, 13:809181.
Jing Hua*, Anna L. Barnett, Gareth J. Williams, Xiaotian Dai, Yuanjie Sun, et al. Association of Gestational Age at Birth With Subsequent Suspected Developmental Coordination Disorder in Early Childhood in China, JAMA Network Open. 2021;4(12):e2137581. doi:10.1001/jamanetworkopen.2021.37581
Zhang J, Williams GJ, Wang G, Chen J, Zhang M, Du W, Zhu J, Zhang J, Hua J*: Early-term birth and its association with universal two-child policy: a national cross-sectional study in China. BMJ Open 2021, 11(12):e054959.
Yuantong Sun, Weiwei Zheng, Ling Zhang, Huijuan Zhao, Xun Li, Chao Zhang, Wuren Ma, Dajun Tian, Kun-Hsing Yu, Shuo Xiao, Liping Jin, Jing Hua*. Quantifying the Impacts of Pre- and Post-Conception TSH Levels on Birth Outcomes: An Examination of Different Machine Learning Models. Front. Endocrinol., 29 October 2021 doi:https://doi.org/10.3389/fendo.2021.755364
Hua J*, Shen J, Zhang J, Zhou Y, Du W, Williams GJ: The association between COVID-19 pandemic and maternal isolated hypothyroxinemia in first and second trimesters. Psychoneuroendocrinology 2021, 128:105210
Liu M, Xue M, Yang Q, Du W, Yan X, Tan J, Duan T, Hua J*: Association between migration status and caesarean section delivery based on a modified Robson classification in China. BMC Pregnancy Childbirth 2021, 21(1):215.
Yang Y, Le Ray I, Zhu J, Zhang J, Hua J*., Reilly M*. Preeclampsia Prevalence, Risk Factors, and Pregnancy Outcomes in Sweden and China. JAMA Netw Open. May 3 2021;4(5):e218401. doi:10.1001/jamanetworkopen.2021.8401
Cao Z, Su X, Ni Y, Luo T, Hua J*. Association between the home environment and development among 3- to 11-month infants in Shanghai, China. Child: care, health and development. Jul 28 2021;doi:10.1111/cch.12902
Zhi-juan Cao, Yan Zhao, Shu-mei Wang, Dong-lan Zhang, Ying-chun Zhou, Wen-na Liu, Ying-ying Yang, Jing Hua*. Prenatal exposure to fine particulate matter and fetal growth: a cohort study from a velocity perspective. Chemosphere 262 (2021) 128404. doi:10.1016/j.chemosphere.2020.128404
Xiujuan Su, Yan Zhao, Yingying Yang, Jing Hua*. Correlation between exposure to fine particulate matter and hypertensive disorders of pregnancy in Shanghai, China. Environ Health. 2020 Sep 17;19(1):101. doi: 10.1186/s12940-020-00655-1.
Zhao Y, Cao Z, Li H, Su X, Yang Y, Liu C, Hua J: Air pollution exposure in association with maternal thyroid function during early pregnancy. J Hazard Mater 2019, 367:188-193.
Cai J, Zhao Y, Kan J, Chen R, Martin R, van Donkelaar A, Ao J, Zhang J, Kan H*, Hua J*. Prenatal Exposure to Specific PM 2.5 Chemical Constituents and Preterm Birth in China: A Nationwide Cohort Study. Environ Sci Technol. 2020 Nov 17;54(22):14494-14501. doi: 10.1021/acs.est.0c02373.
Yan Zhao , Jing Cai, Xinlei Zhu, Aaron van Donkelaar , Randall V Martin, Jing Hua*, Haidong Kan*. Fine particulate matter exposure and renal function. Environ Int. 2020 Aug;141:105805. doi:10.1016/j.envint.2020.105805. Epub 2020 May 29
Jing Hua*, Wenchong Du*, Xiaotian Dai, Meiqin Wu, Xianying Cai, Min Shen, Liping Zhu International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation. Developmental Medicine & Child Neurology, 2020. DOI: 10.1111/dmcn.14693
Jiajun Lyu, Qingqing Zhu, Shilu Tong, Xiujuan Su, Shenghui Li*, Jing Hua* Trajectories of sleep quality and associations with excessive gestational weight gain during pregnancy. Sleep and Biological Rhythms. 2020, March, https://doi.org/10.1007/s41105-020-00266-w
Jing Hua*, Yu Li, Kan Ye,Yujie Ma,Senran Lin , Guixiong Gu, Wenchong Du. The reliability and validity of Bayley-III cognitive scale in China’s male and female children. Early Human Development. 2019,129,71-78.
Jing Hua*, Jie Sun, Zhijuan Cao, Xiaotian Dai, Senran Lin, Jialin Guo, Guixiong Gu, Wenchong Du. Differentiating the cognitive development of early-term births in infants and toddlers: a cross-sectional study in China. BMJ Open 2019, 2019 Apr 11;9(4): e025275.
Yang Y, Yang T, Liu S, Cao Z, Zhao Y, Su X, Liao Z, Teng X, Hua J*. Concentrated ambient PM2.5 exposure affects mice sperm quality and testosterone biosynthesis. PeerJ. 2019 Nov 28;7:e8109. doi: 10.7717/peerj.8109. eCollection 2019.
Mei-Qin Wu*, Jin Liu*, Ya-Qian Wang, Ying Yang, Chong-Huai Yan, Jing Hua*. The Role of Thyroid Screening in Pregnancy. Frontiers in Endocrinology 2019, 8(10)Article522
Cao Z#, Meng L#, Zhao Y, Liu C2, Yang Y, Su X, Fu Q, Wang D, Hua J*.
Maternal exposure to ambient fine particulate matter and fetal growth in Shanghai, China. Environ Health. 2019 May 16;18(1):49. doi: 10.1186/s12940-019-0485-3.
Zhao Y, Wang L, Liu H, Cao Z, Su X, Cai J, Hua J*. Particulate Air Pollution Exposure and Plasma Vitamin D Levels in Pregnant Women: A Longitudinal Cohort Study. J Clin Endocrinol Metab. 2019 Mar 21. pii: jc.2018-02713. doi: 10.1210/jc.2018-02713. [Epub ahead of print]
Xiujuan Su, Yan Zhao, Zhijuan Cao, Yingying Yang, Tony Duan*, Jing Hua*. Association between isolated hypothyroxinaemia in early pregnancy and perinatal outcomes. Endocr Connect. 2019 Mar 1. pii: EC-19-0088. doi: 10.1530/EC-19-0088. [Epub ahead of print]
Yan Zhao, Zhijuan Cao, Huichu Li Xiujuan Sua, Yingying Yanga, Chao Liu, Jing Hua*. Air pollution exposure in association with maternal thyroid function during early pregnancy. Journal of Hazardous Materials. 2019 Apr 5;367:188-193. doi: 10.1016/j.jhazmat.
Zhijuan Cao#, Jinghua(co-first athor)#, Donglan Zhang, Janani R Thapa, Shumei Wang*. A cohort study assessing the sustainable long-term effectiveness of childhood-obesity intervention in China. International Journal of Epidemiology. Int J Epidemiol. 2018 Jul 25. doi: 10.1093/ije/dyy14
Jing Hua*, Liping Zhu*, Li Du, Yu Li, Zhuochun Wu, Da Wo and Wenchong Du. Effects of midwife-led maternity services on postpartum wellbeing and clinical outcomes in primiparous women under China’s one-child policy. BMC Pregnancy and Childbirth. 2018, 18:329. https://doi.org/10.1186/s12884-018-1969-95
Jing Hua*, Tao Duan, Guixiong Gu, Qingqing Zhu, Jiang-Qin Liu, Zhuochun Wu. Wei Meng. Effects of home and education environments on children's motor performance in China [J]. Developmental Medicine & Child Neurology, 2016, Aug; 58(8):868-876.
Jing Hua*, Liping Zhu*, Wenchong Du , Li Du, Ting Luo, Zhuochun Wu. Infant’s sex, birth control policy and postpartum well-being: a prospective cohort study in Shanghai, China. BMJ Open. 2016;6:e012207.doi:10.1136/bmjopen-2016-012207
Zhewei Wang, Jing Hua (Co-first author), Xu Yuhong. The Relationship between Gentle Tactile Stimulation on the Fetus and Its Temperament 3 Months after Birth. Behav Neurol. 2015; 2015:371906.doi: 10.1155/2015/371906. Epub 2015 May 28.
Jing Hua*, Guixiong Gu#, Qingqing Zhu#, Da Wo, Ming Liu, Jiang-Qin Liu, Jie Mao, Tao Duan*. The reliability and validity of the Developmental Coordination Disorder Questionnaire'07 for children aged 4-6 years in mainland China[J]. Research in Developmental Disabilities, 2015, Dec; 47:405-415
Jing Hua*, Fuhai Geng, Li Peng, Zhuo Chun Wu, Guanghua Wan. Differentiation the acute effects of Black Carbon and PM2.5 on blood pressure during pregnancy. Journal of the American College of Cardiology, Abs. Volume 66(16), Suppl, 2015, October , 66(16) C119-C120
Jing Hua, Guixiong Gu, Peiqi Jiang , Lijun Zhang, Liping Zhu*, Wei Meng*. The prenatal, perinatal and neonatal risk factors for children's developmental coordination disorder: A population study in mainland China[J], Research in Developmental Disabilities, 2014, March,35(3), 619-625
Jing Hua*, Hua Jin, Li Du, Lijun Zhang, Guixiong Gu , Zhuochun Wu. The influence of one-child status in Chinese families on Developmental Coordination Disorder status, Research in Developmental Disabilities, 2014,Aug 16,35(11):3089-3095.
Jing Hua, Yong Yin, Li Peng, Li Du, Fuhai Geng, Liping Zhu*.Acute effects of black carbon and PM2.5 on children asthma admissions: a time-series study in Chinese city[J], Science of the Total Environment. 2014, May ,15,481:433-438.
Jing Hua*, Guixiong Gu,Wei Meng, Zhuochun Wu. Child neglect in one-child family from Suzhou City of Mainland China. BMC International Health and Human Rights[J]. BMC Int Health Hum Rights. 2014,Mar 25,14(1):8.
Jing Hua, Guixiong Gu*, Wei Meng, Zhuochun Wu. Age band 1 of the Movement Assessment Battery for Children-Second Edition: exploring its usefulness in mainland China [J]. Research in Developmental Disabilities, 2013, Feb,34(2):801-808.
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