主持或参加科研课题:
1.国家自然科学基金委员会,面上项目,82171179,小胶质细胞SIRT1调节糖尿病慢性脑低灌注相关认知功能障碍的作用与机制研究,2022-01至2025-12,55万元,在硏,负责人
2.国家自然科学基金委员会,面上项目,81871103,TREM2-TLR4介导的神经炎症在糖尿病慢性脑低灌注认知功能障碍中的作用及机制,2019-01至2022-12,56万元,结题,负责人
3.国家自然科学基金委员会,面上项目,81672243,线粒体自噬在糖尿病慢性脑低灌注动物认知功能障碍中的作用及高压氧保护机制,2017-01至2020-12,57万元,结题,负责人
4.国家自然科学基金委员会,国际(地区)合作与交流项目NSFC-NRF(中韩),61811540411,基于机器学习的多模态医学影像分析与脑疾病诊断,2018-07至2020-06,10万元,结题,第二参与人
5.国家自然科学基金委员会,面上项目,61375112,基于深度学习的多模态神经影像融合分析与脑疾病诊断,2014-01至2017-12,76万元,结题,第二参与人
6.上海市科委,医学引导类科技项目,134119a9700,融合结构和功能神经影像技术对老年性痴呆的早期筛查及鉴别,2013-10至2016-09,10万元,结题,负责人
Lead or participate in scientific research projects:
1. National Natural Science Foundation of China, general project, 82171179, the role and mechanism of microglia SIRT1 in regulating cognitive dysfunction related to chronic cerebral hypoperfusion in diabetes, 2022-01 to 2025-12, 550000 yuan, in research, person in charge
2. National Natural Science Foundation of China, general project, 81871103, the role and mechanism of TREM2-TLR4 mediated neuroinflammation in cognitive dysfunction of chronic cerebral hypoperfusion in diabetes, January 2019 to December 2022, 560000 yuan, completed, person in charge
3. National Natural Science Foundation of China, general project, 81672243, the role of mitochondrial autophagy in cognitive dysfunction of diabetes chronic cerebral hypoperfusion animals and hyperbaric oxygen protection mechanism, January 2017 to December 2020, 570000 yuan, completed, person in charge
4. National Natural Science Foundation of China, International (Regional) Cooperation and Exchange Project NSFC-NRF (China Korea), 61811540411, Multi modal Medical Imaging Analysis and Brain Disease Diagnosis Based on Machine Learning, July 2018 to June 2020, 100000 yuan, completed, second participant
5. National Natural Science Foundation of China, General Project 61375112, Multi modal neuroimaging fusion analysis and brain disease diagnosis based on deep learning, 760000 yuan from January 2014 to December 2017, completed, second participant
6. Shanghai Municipal Science and Technology Commission, Medical Guidance Science and Technology Project, 134119a9700, Early Screening and Differentiation of Alzheimer's Disease by Integrating Structural and Functional Neuroimaging Technology, October 2013 to September 2016, 100000 yuan, completed, responsible person
发表论文(2018-2023):
(1) Cell Death and Disease.2023 Nov 06;14:721. (IF:9.685)
(2) Front Aging Neurosci. 2022 Sep 29;14:1004557.(IF:5.702)
(3) Int Immunopharmacol. 2022 Jul;108:108756.(IF:5.714)
(4) J Neuroinflammation. 2021 Sep 16;18(1):207.(IF:9.587)
(5) Int Immunopharmacol. 2021 Jul;96:107808. (IF:5.714)
(6) Int Immunopharmacol. 2021 Apr;93:107422. (IF:5.714)
(7) Mediators Inflamm. 2020 Dec18;2020:7974537. (IF:4.711)
(8) Life Sci.2020 Mar 1;244:117322. (IF:5.037)
(9) J Neuroinflammation. 2020 Jan 3;17(1):2. (IF:8.322)
(10) Front Pharmacol. 2020 Jun 19;11:934.(IF:5.81)
(11) Mol Immunol. 2019 Oct 03; 116:29-37.(IF:4.407)
(12) Neuroscience. 2019 Nov 1:419:121-128.(IF:3.244)
(13) Mol Neurobiol. 2018 Jan;55(1):776-791. (IF:5.590)
(14) Sci Rep. 2018 Feb 19;8(1):3301. (IF:4.011)
(15) J Photochem Photobiol B. 2018 Jul;184:1-6. (IF:4.383)
(16) Brain Res Bull. 2018 Jun:140:1-4.(IF:3.44)
(17)Curr Alzheimer Res. 2018;15(10):917-927.(IF:3.289)