1.炎症性皮肤病（银屑病）的发病机制研究，包括角质形成细胞、T细胞的生物学功能，皮肤微生物调控等；
2.皮肤疾病（银屑病）治疗药物探索。
1. Research on the pathogenesis of inflammatory skin diseases (psoriasis), including the biological functions of keratinocytes and T cells, and the regulation of skin microbiota;
2. Exploration of therapeutic drugs for skin diseases (psoriasis).
上海市第十人民医院助理研究员；同济大学医学院银屑病研究所PI。
Assistant Researcher, Shanghai Tenth People's Hospital; Principal Investigator, Institute of Psoriasis, Tongji University School of Medicine.
共发表SCI论文20余篇；授权发明专利5项；主持国自然科学基金2项。
代表性论著如下：
1. Huizi Xiong, Zengyang Yu. Association between systemic inflammation indicators and psoriasis: a cross-sectional study from NHANES. Frontiers in Immunology, 2025, 16:1556487.
2. Zengyang Yu, Xinyi Tang, Zeyu Chen, Yifan Hu, Shuqin Zhang, Chunyuan Guo, Jun Gu, Yuling Shi, Yu Gong. Role of ADAM10/17-Mediated Cleavage of LAG3 in the Impairment of Immunosuppression in Psoriasis. Journal of Investigative Dermatology. 2024, 20: S0022-202X(24)02948-8.
3. Zengyang Yu, Qian Yu, Hui Xu, Dai, Xing, Yingyuan Yu, Lian Cui, Youdong Chen, Jun Gu, Xilin Zhang, Chunyuan Guo, Yuling Shi. IL-17A Promotes Psoriasis-Associated Keratinocyte Proliferation through ACT1-Dependent Activation of YAP-AREG Axis. Journal of Investigative Dermatology, 2022, 142(9): 2343–2352.
4. Zengyang Yu, Yu Gong, Lian Cui, Yifan Hu, Qianqian Zhou, Zeyu Chen, Yingyuan Yu, Youdong Chen, Peng Xu, Xilin Zhang, Chunyuan Guo, Yuling Shi. High-throughput transcriptome and pathogenesis analysis of clinical psoriasis. Journal of Dermatological Science, 2020, S0923-1811(20)30115-8.
