1. 皮肤感染与免疫相关疾病；2. 超灵敏数字生物分析技术；3. 功能纳米微球的制备研究

1. Cutaneous Infections and Immune-Mediated Disorders; 2. Ultrasensitive Digital Bioassay Technologies; 3. Engineered Functional Nanobeads: Design, Synthesis and Characterization

张鹏飞，博士，硕士研究生导师，就职于同济大学附属皮肤病医院，中心实验室。

中国分析测试协会纳米分析专委会委员；白求恩精神研究会医学人文分会常务理事；白求恩精神研究会检验医学分会常务理事；白求恩精神研究会区域专委会常务委员；中国微纳米学会高级会员；中国生物化学与分子生物学会终身会员；中国化学会会员；美国化学会会员；Sigma Xi会员等。

带领团队先后荣获同济大学十大最具转化潜力项目入围奖；微纳系统与工程(MINE)青年科学家入围奖；苏州金鸡湖创业大赛华东区总决赛等荣誉称号。主持完成国家自然科学基金，上海市自然基金，上海市“科技创新行动计划”生物医药专项基金等课题多项，第一或通讯发表Analytical Chemistry等SCI论文20余篇，申请发明专利10项，授权5项，其中国际PCT专利2项。

Pengfei Zhang, Ph.D.

Central Laboratory, Affiliated Dermatology Hospital, Tongji University, Shanghai 200443, China

Professional Affiliations

- Committee Member, Nano-Analysis Specialty Committee, China Association for Instrumental Analysis

- Executive Director, Medical Humanities Branch, Norman Bethune Spirit Research Association

- Executive Director, Laboratory Medicine Branch, Norman Bethune Spirit Research Association

- Standing Committee Member, Regional Specialty Committee, Norman Bethune Spirit Research Association

- Senior Member, Chinese Society of Micro-Nano Technology

- Life Member, Chinese Society of Biochemistry and Molecular Biology

- Member, Chinese Chemical Society

- Member, American Chemical Society

- Member, Sigma Xi (The Scientific Research Honor Society)

Honors & Awards (selected)

- Top-10 Translational-Potential Projects, Tongji University

- Finalist, Young Scientist Award, International Conference on Micro- & Nano-systems for Engineering (MINE)

- Finalist, Suzhou Jinji Lake Entrepreneurship Competition (East-China Regional Finals)

Research Funding (Principal Investigator)

- National Natural Science Foundation of China (completed)

- Shanghai Natural Science Foundation (completed)

- Shanghai “Sci-Tech Innovation Action Plan” – Biomedical Special Program (completed)

Publications & Patents

- >20 SCI papers as first or corresponding author in journals including Analytical Chemistry

- 10 invention patent applications filed, 5 granted (including 2 international PCT patents)

【发表文章】

Wenwen Xia#, Ying Wu#, Xiangyi Liao#, Lili Cui, Huanxing Han, Juanjuan Hou, Zhipeng Wang*, Pengfei Zhang*, Shouhong Gao*, On-Site Therapeutic Drug Monitoring for Program Death-1 Antibody Using a Quantum Dot Nanobeads-Based Lateral Flow Immunoassay, Anal. Chem. 2025, 27, 14612–14619.

Xiaoyi Li, Wannian Yan, Yucheng Wang, Ru-jia Yu, Huanxing Han, Pengfei Zhang*, Plasmon-Enhanced Quantum Dot Nanobead-Based Lateral Flow Assay with Lower Background and Improved Sensitivity, ACS Applied Nano Materials, 2025, 8(8), 4120-4128.

Lingzhi Fan, Wannian Yan, Qilong Chen, Fei Tan, Yijie Tang, Huanxing Han, Rujia Yu, Ni Xie, Shouhong Gao, Wansheng Chen*, Zhongjian Chen*, Pengfei Zhang*, One-Component Dual-Readout Aggregation-Induced Emission Nanobeads for Qualitative and Quantitative Detection of C-Reactive Protein at the Point of Care, Anal. Chem. 2024, 96(1), 401–408.

Lingzhi Fan#, Jing Yang#, Jianbing Wu#, Fugang Li, Wannian Yan, Fei Tan, Madeline Zhang, Mohamed S. Draz*, Huanxing Han*, Pengfei Zhang*, Deeply-dyed nanobead system for rapid lateral flow assay testing of drugs at point-of-care, Sensors and Actuators B: Chemical, 2022, 362, 131829.

Wannian Yan#; Lingzhi Fan#; Jin Li#; Yijiang Wang; Huanxing Han; Fei Tan*; Pengfei Zhang*; Bimodal size distribution immuno-quantum dots for fluorescent western blotting assay with high sensitivity and extended dynamic range, Microchimica Acta, 2020, 187, 598.

【专利】

1、一种多重指标数字检测样本的系统、方法及应用，申请号：2025104187138。

2、一种基于数字层析和CRISPR系统的无扩增超灵敏核酸检测系统及检测方法，申请号：CN202411101442.5。

3、一种多模式聚集诱导荧光免疫层析试纸及其制备方法，授权号：ZL202210285423.7。

4、一种彩色乳胶颗粒、复合物、免疫层析试纸及其制备方法，授权号：ZL 202110766151.8。

5、ULTRA-SENSITIVE DIGITAL RAPID CHROMATOGRAPHIC DETECTION SYSTEM AND METHOD FOR ANALYTE,申请号US202118022994A。

6、超灵敏数字层析快速检测分析物的系统及方法，授权号：ZL 2020108603286。