上海市皮肤病医院光医学治疗科青年PI,带领团队构建首例亚洲人来源的永生化皮脂腺细胞系,在Protein Cell(2019,2023),J Am Acad Dermatol(2023,2024),J Eur Acad Dermatol Venereol ,Phytomedicine,Cell Mol Life Sci, Oncoimmunology等国际有影响力的杂志发表多篇SCI论文。
近五年主持项目:
国自然面上项目(55万);
国自然青年基金(30万);
上海市科委面上项目(20万);
上海市皮肤病医院学术骨干项目(30万);
中国博士后基金(5万);
另外作为项目骨干参与科技部国家重点研发计划皮肤肿瘤专项课题和多项国自然面上项目。
代表论著:
Wu Y, Yan Y, Zhang L, Liu X, Yang J, Cao Y, Chang Q, Yan J, Zeng Q, Wang P, Wang X. Positive results of intense pulsed light-photodynamic therapy for moderate-to-severe rosacea: A prospective, single-arm study. J Am Acad Dermatol. 2024 Jul 5:S0190-9622(24)01002-8.
Liu J, Xu D, Yan J, Wang B, Zhang L, Liu X, Zhang H, Yan G, Yang J, Zeng Q, Wang X. A novel H‑tert immortalized human sebaceous gland cell line (XL-i-20) for the investigation of photodynamic therapy. Photodiagnosis Photodyn Ther. 2024 Jun 6;48:104238.
Kang Z, Wang P, Wang B, Yan Y, Zhao Z, Li C, Wen L, Wu M, Yan G, Wang X, Zhang G, Zeng Q. Echinatin suppresses cutaneous squamous cell carcinoma by targeting GSTM3-mediated ferroptosis. Phytomedicine. 2024 Aug;131:155752.
Feng C, Zhang H, Wang P, Zhang L, Liu X, Yan G, Yan Y, Yang J, Liu J, Tan F, Wang X, Zeng Q. Oroxylin A suppress LL-37 generated rosacea-like skin inflammation through the modulation of SIRT3-SOD2-NF-κB signaling pathway. Int Immunopharmacol. 2024 Mar 10;129:111636.
Yang J, Liu X, Cao Y, Wang P, Zhang H, Chen Q, Yang Y, Zeng Q, Zhang L, Wang X. 5-Aminolevulinic acid photodynamic therapy versus minocycline for moderate-to-severe rosacea: A single-center, randomized, evaluator-blind controlled study. J Am Acad Dermatol. 2023 Jun 24.
Cheng Y, Lu X, Li F, Chen Z, Zhang Y, Han Q, Zeng Q, Wu T, Li Z, Lu S, Williams C, Xia W. NDFIP1 limits cellular TAZ accumulation via exosomal sorting to inhibit NSCLC proliferation. Protein Cell. 2023 Mar 16;14(2):123-136.
Zeng Q, Yang J, Ji J, Wang P, Zhang L, Yan G, Wu Y, Chen Q, Liu J, Zhang G, Wang X. PD-L1 blockade potentiates the antitumor effects of ALA-PDT and optimizes the tumor microenvironment in cutaneous squamous cell carcinoma. Oncoimmunology. 2022 Apr 3;11(1):2061396.
Zeng Q, Yang J, Yan G, Zhang L, Wang P, Zhang H, Chen Q, Cao Y, Liu X, Wang X. Celastrol inhibits LL37-induced rosacea by inhibiting Ca2+/CaMKII-mTOR-NF-κB activation. Biomed Pharmacother. 2022 Sep;153:113292.
Wu YH, Wu F, Yan GR, Zeng QY, Jia N, Zheng Z, Fang S, Liu YQ, Zhang GL, Wang XL. Features and clinical significance of tertiary lymphoid structure in cutaneous squamous cell carcinoma. J Eur Acad Dermatol Venereol. 2022 Nov;36(11):2043-2050.
Cheng Y, Zeng Q, Han Q, Xia W. Effect of pH, temperature and freezing-thawing on quantity changes and cellular uptake of exosomes. Protein Cell. 2019 Apr;10(4):295-299.
Zeng Q, Zhang H, Qin J, Xu Z, Gui L, Liu B, Liu C, Xu C, Liu W, Zhang S, Huang S, Chen L. Rapamycin inhibits BAFF-stimulated cell proliferation and survival by suppressing mTOR-mediated PP2A-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells. Cell Mol Life Sci. 2015 Dec;72(24):4867-84.