超声医学:超声新技术在肺部疾病诊断与介入治疗中的应用 Ultrasound medicine: Ultrasound diagnosis and interventional treatment of pulmonary diseases
1、中国医促会结核病防治分会超声学组副组长Deputy leader of ultrasound group, Tuberculosis control branch, China Medical Care International Exchange Promotion Association;
2、上海市超声医学工程学会介入专委会副主任委员Deputy chairman of intervention committee of Shanghai ultrasonic medical engineering society;
3、中国医师协会介入医师分会超声介入专委会胸部介入学组副主任委员Vice Chairman of thoracic Interventional Therapy Group, Ultrasound Interventional Therapy Special Committee, Interventional Physician Branch, Chinese Medical Doctors Association;
4、亚太基层卫生协会超声医学分会重症超声专业委员会副主任委员Vice Chairman of the professional Committee of critical Ultrasound of the Ultrasound Medicine Branch of the Asia Pacific Primary Health Association;
5、中国医学装备协会超声分会远程及移动超声专委会常委Standing committee member of remote and mobile ultrasound committee of China medical equipment association ultrasound branch;
6、中国医药教育协会超声专业委员会重症超声学组常委Standing committee of severe ultrasound group, ultrasound professional committee, China medical education association;
7、上海市超声医学工程学会理事Director of Shanghai ultrasonic medical engineering society;
8、中国医促会结核病防治分会第二届委员The Second Session Committee Member of TB Prevention and Treatment Branch of China International Exchange and Promotive Association for Medical and Health Care;
9、中国医师协会介入医师分会超声介入青委会委员The Committee Member of Ultrasound Intervention Youth Committee of Chinese College of Interventionalists;
10、中国医学装备协会超声装备技术分会第二届委员
聚焦肺癌与肺结核的超声诊断与治疗,探索超声新技术以及人工智能在肺部疾病诊断与治疗中的应用。近期在研科研课题全部围绕肺超声进行。 主持及参与科研课题10余项,其中主持课题4项(省部级2项),目前在研科研经费共210万元。
主持的在研科研项目:
1.上海市科委项目:常规超声联合超声造影技术在肺结核诊断中的应用(18411966700,20万元,2018-2021)2018 Supporting Project of Medical Guidance (Chinese and Western Medicine) of Science and Technology Commission of Shanghai Municipality (18411966700);
2.上海市科委项目:人工智能辅助超声诊断胸膜下肺病灶的技术标准和应用研(19DZ2203300,30万元,2019-2022)2019 Technical Standard Project of Shanghai "Science and Technology Innovation Action Plan" of Science and Technology Commission of Shanghai Municipality (19DZ2203300);
3.上海市肺科医院临床研究基金:胸膜下肺病灶超声图像分割与诊断的人工智能神经网络系统开发与应用研究(fk1940,60万元,2019-2021)Clinical Research Foundation of ShangHai Pulmonary Hospital (fk1940);
4、上海市肺科医院临床研究基金:超声引导经皮肺穿刺活检术在胸膜下肺部病变诊断中的价值:一项前瞻性、多中心队列研究(FKLY20015,100万元,2020-2023)Clinical Research Foundation of ShangHai Pulmonary Hospital (FKLY20015)
已完成的科研项目:
1、国家自然科学基金面上项目,microRNA-103-3p心肌靶向表达通过下调TLR4改善心梗后慢性心力衰竭的研究(81370348,75万元,2014-2017);
2、上海市科委项目:超声靶向微泡破碎介导microRNA-378心肌组织特异性表达的研究(13ZR1409400,10万元,2013-2016);
3、第二军医大学附属长海医院“1255”科研基金:循环肿瘤细胞检测在中晚期乳腺癌的临床应用研究的子课题:乳腺癌靶向超声造影剂制备的方法学研究(5万元,2013-2015);
4、国家自然科学基金青年科学基金项目:基于超声背散射信号成像的脊柱侧凸椎弓根螺钉植入导航(81101396,,22万元,2012-2014);
5、 国自然青年基金:超声背散射信号评价椎弓根螺钉钉道周围骨密度及骨微结构的方法研究(81601953,17万元,2017-2019)
在国内外核心期刊发表论文共50篇(第一/通讯作者),其中SCI 12篇,总分值45.59分,单篇最高6.97分。
1、Xu Y#, Zhang Y#, Bi K#, Ning Z, Xu L, Shen M, Deng G*, Wang Y*, Boundary Restored Network for Subpleural Pulmonary Lesion Segmentation on Ultrasound Images at Local and Global Scales, J Digit Imaging, 2020 (通讯作者,IF: 3.697);
2、 Zhang C#, Xu L#, Deng G#, Ding Y, Bi K, Jin H, Shu J, Yang J, Deng H, Wang Z*, Wang Y*, Exosomal HOTAIR promotes proliferation, migration and invasion of lung cancer by sponging miR-203, Sci China Life Sci, 2020 (通讯作者,IF: 3.58);
3、Chen Wang#, Xuren Wang#, Xisha Long, Demeng Xia, Daofeng Ben, Yin Wang*, Publication trends of research on acute lung injury and acute respiration distress syndrome during 2009-2019: a 10-year bibliometric analysis (通讯作者,IF: 3.375);
4、Volume Navigation with Fusion of Real-Time Ultrasound and CT Images to Guide Posterolateral Transforaminal Puncture in Percutaneous Endoscopic Lumbar Discectomy(共同第一,SCI,IF:2.556);
5、Ultrasound-controlled DOX-SiO2 nanocomposites enhance the antitumour efficacy and attenuate the toxicity of doxorubicin(第一作者,SCI,IF:6.97);
6、Up-regulated TLR4 in cardiomyocytes exacerbates heart failure after long-term myocardial infarction(共同第一,SCI,IF:4.938,被引7次);
7、Exchangeability of FITC-SiO₂ Nanoparticles Between Cancer Cells Increases the Range of Drug Delivery(共同通讯,SCI,IF:5.068);
8、Inhibition of Cancer Cell Migration with CuS@mSiO2-PEG Nanoparticles by Repressing MMP-2/MMP-9 Expression.International Journal of Nanomedicine.(共同通讯,SCI,IF:4.37);
9、Porous Se@SiO2 nanocomposites protect the femoral head from methylprednisolone-induced osteonecrosis,(共同通讯,SCI,IF:4.37,被引1次);
10、Salusins protect myocardium against ischemic injury by alleviating endoplasmic reticulum stress(共同第一作者,SCI,IF:1.688,被引3次);
11、Exosomal HOTAIR promotes proliferation, migration and invasion of lung cancer by sponging miR-203, Sci China Life Sci, 2020 (通讯作者,SCI,IF: 3.58);
12、常规超声联合超声造影在胸膜下肺结核与细菌性肺炎鉴别诊断中的应用价值(通讯作者);
13、超声造影引导下经皮肺穿刺活检在菌阴肺结核诊断中的应用价值(通讯作者);
14、超微血流成像技术在颈部淋巴结结核分型诊断中的应用价值(通讯作者);
15、胸膜结核瘤常规超声及超声造影表现初步探讨(通讯作者);
16、结核病超声诊断现状与思考(第一作者);
17、超声技术在2019-冠状病毒病诊治中的应用(第一作者);
18、超声造影在胸膜下肺结核与肺癌鉴别诊断中的价值(通讯作者);
19、胸腔超声造影在胸腔积液闭式引流治疗中的应用价值(通讯作者);
20、超声弹性成像在颈部淋巴结结核诊断中的价值(通讯作者);
21、超声新技术在肺结核诊断中的应用进展(通讯作者);
22、超声技术在2019-冠状病毒病诊治中的应用(第一作者);
23、超声新技术在结核病诊断中的应用(第一作者);
24、计算机辅助诊断技术在超声医学中的应用进展(通讯作者);
25、超声引导下经皮肺穿刺1444例并发症分析(通讯作者);
26、超声造影引导下经皮穿刺取材在浅表淋巴结结核诊断中的价值(共同通讯作者)