方向一：椎间盘退变

方向二：脊柱微创手术智能化导航

Direction 1: Intervertebral Disc Degeneration

Direction 2: Intelligent Navigation for Minimally Invasive Spinal Surgery

同济大学附属第十人民医院骨科主任、脊柱外科主任、脊柱微创中心主任、同济大学脊柱疼痛医学研究所所长。兼任亚太脊柱微创协会理事、国家卫计委脊柱内镜诊疗技术专家组委员、中国医师协会骨科医师分会脊柱疼痛专业委员会主任委员、中国医师协会疼痛科医师分会脊柱疼痛专业委员会副主任委员、中国医师协会疼痛科医师分会脊柱疼痛微创工作组组长、中国医师协会骨科医师分会脊柱显微学组副组长、中华医学会骨科分会微创学组委员、中国医师协会骨科医师分会微创脊柱专业委员会委员、中国医师协会内镜医师学分会委员、中国医师协会内镜医师分会脊柱内镜专业委员会常委、中国康复医学会颈椎病专业委员会常委、中国康复医学会脊柱脊髓专业委员会委员、中国非公立医疗机构协会骨科专业委员会常委、中国医促会骨科疾病防治专业委员会脊柱内镜学组副组长、中国医药教育协会脊柱微创学组副组长、中国康复医学会脊柱脊髓专业委员会微创脊柱外科学组委员、中华医学会老年学分会老年脊柱学组委员、上海市康复医学会脊柱脊髓专业委员会副主任委员、上海市医学会骨科专业委员会委员、上海市医师协会骨科医师分会委员、上海市医学会骨科分会微创学组副组长、上海市康复医学会第六届理事会理事、《中华外科杂志》通讯编委、《中华骨科杂志》通讯编委、《中国矫形外科杂志》编委、《中国脊柱脊髓杂志》青年编委等职务。

Prof. He serves as the Director of Orthopedics, Director of Spinal Surgery, Director of Minimally Invasive Spine Center at Tenth People’s Hospital Affiliated to Tongji University, and Director of Spinal Pain Research Institute at Tongji University. He also serves as a member of the Asia-Pacific Minimally Invasive Spine Association, a member of the Expert Committee on Spinal Endoscopic Diagnosis and Treatment Technology of the National Health and Family Planning Commission, Chairman of the Spinal Pain Professional Committee of the Chinese Medical Doctor Association Orthopedic Physicians Branch, Deputy Chairman of the Spinal Pain Professional Committee of the Pain Physicians Branch of the Chinese Medical Doctor Association, Head of the Minimally Invasive Spinal Pain Working Group of the Pain Physicians Branch of the Chinese Medical Doctor Association, Deputy Group Leader of the Spinal Microscopy Group of the Orthopedic Physicians Branch of the Chinese Medical Doctor Association, Member of the Minimally Invasive Group of the Orthopedic Branch of the Chinese Medical Association, Member of the Minimally Invasive Spine Professional Committee of the Orthopedic Physicians Branch of the Chinese Medical Doctor Association, Member of the Endoscopic Physicians Branch of the Chinese Medical Doctor Association, Standing Committee Member of the Endoscopic Spinal Professional Committee of the Endoscopic Physicians Branch of the Chinese Medical Doctor Association, Standing Committee Member of the Cervical Spondylosis Professional Committee of the Chinese Association of Rehabilitation Medicine, Member of the Spine and Spinal Cord Professional Committee of the Chinese Association of Rehabilitation Medicine, Standing Committee Member of the Orthopedic Professional Committee of the China Association of Non-Governmental Medical Institutions, Deputy Group Leader of the Spinal Endoscopy Group of the Medical Promotion Association Bone Disease Prevention and Treatment Professional Committee, Deputy Group Leader of the Spinal Minimally Invasive Group of the Chinese Medical Education Association, Member of the Minimally Invasive Spinal Surgery Group of the Spine and Spinal Cord Professional Committee of the Chinese Association of Rehabilitation Medicine, Member of the Geriatric Spine Group of the Geriatrics Branch of the Chinese Medical Association, Deputy Chairman of the Spine and Spinal Cord Professional Committee of the Shanghai Rehabilitation Medical Association, Member of the Orthopedic Professional Committee of the Shanghai Medical Association, Member of the Orthopedic Physicians Branch of the Shanghai Medical Doctor Association, Deputy Group Leader of the Minimally Invasive Group of the Orthopedic Branch of the Shanghai Medical Association, Member of the Sixth Council of the Shanghai Rehabilitation Medical Association, Corresponding Editor of the Chinese Journal of Surgery, Corresponding Editor of the Chinese Journal of Orthopedics, Editorial Board Member of the Chinese Journal of Orthopedic Surgery, and Young Editorial Board Member of the Chinese Journal of Spine and Spinal Cord.

至今已在国内核心期刊发表中文论著100余篇，英文SCI论著100余篇。获国家教育部优秀归国留学人员科研启动基金、国家自然科学基金、上海市基础研究重点项目及军队十一五国际合作项目等多项基金资助。获上海市及军队各类奖共十余项，其中《脊柱侧凸三维矫形新技术及临床应用》获上海市科技进步一等奖，《颈椎病的外科治疗和相关基础研究》获得军队医疗成果二等奖，《微创新技术在脊柱外科中的应用及相关研究》获上海市医学科技进步二等奖，《脊柱微创手术中减少射线暴露及快速定位的关键技术及应用》获上海技术发明二等奖。

主编专著：《脊柱微创外科技术》（2006年）、《微创腰椎融合术》（2010年）、《脊柱常见疾病微创治疗与康复》（2010年）、《V形双通道脊柱内镜技术》（2021）、《V-Shape Bichannel Endoscopy: Technique and Practice》（2023年），其中《脊柱微创外科技术》是国内第一部脊柱微创专著。

Prof. He has published over 100 Chinese articles in domestic core journals and over 100 English SCI articles. He has received funding from various sources, including the Excellent Returnees Research Start-up Fund from the Ministry of Education, the National Natural Science Foundation, the Key Basic Research Project of Shanghai, and an international cooperation project during the Eleventh Five-Year Plan period of the military. He has won over ten awards from Shanghai and the military, including the Shanghai Science and Technology Progress First Prize for "New Technology and Clinical Application of Three-Dimensional Correction for Spinal Scoliosis," the Second Prize for Military Medical Achievements for "Surgical Treatment and Related Basic Research of Cervical Spondylosis," the Second Prize for Medical Science and Technology Progress in Shanghai for "Application and Related Research of Minimally Invasive Techniques in Spinal Surgery," and the Second Prize for Shanghai Technical Invention for "Key Technologies and Applications for Reducing Radiation Exposure and Rapid Localization in Minimally Invasive Spinal Surgery."

Prof. He has edited several monographs, including "Minimally Invasive Spinal Surgery Techniques" (2006), "Minimally Invasive Lumbar Fusion Surgery" (2010), "Minimally Invasive Treatment and Rehabilitation of Common Spinal Diseases" (2010), "V-Shaped Bichannel Spinal Endoscopy Techniques" (2021), and "V-Shape Bichannel Endoscopy: Technique and Practice" (2023). Among them, "Minimally Invasive Spinal Surgery Techniques" is the first monograph on minimally invasive spinal surgery in China.

Representative Publications：

1.Cao W, Wang Z, Liu X, Zhou Z, Zhang Y, He S *, Cui D *, Chen F *. Bioinspired MXene-Based User-Interactive Electronic Skin for Digital and Visual Dual-Channel Sensing. Nanomicro Lett. 2022 May 3;14(1):119.

2.Zhou X, Yan N, Cornel EJ, Cai H, Xue S, Xi H, Fan Z *, He S *, Du J *. Bone-targeting polymer vesicles for simultaneous imaging and effective malignant bone tumor treatment. Biomaterials. 2021 Feb; 269:120345.

3.Feng C, Lu BQ*, Fan Y, Ni H, Zhao Y, Tan S, Zhou Z, Liu L, Hachtel JA, Kepaptsoglou D, Wu B, Gebauer D, He S*, Chen F*. Amorphous 1-D nanowires of calcium phosphate/pyrophosphate: A demonstration of oriented self-growth of amorphous minerals. J Colloid Interface Sci. 2024 Mar; 657:960-970.

4.Zhou Z, Fan Y, Jiang Y, Shi S, Xue C, Zhao X, Tan S, Chen X, Feng C, Zhu Y, Yan J, Zhou Z, Zhao Y, Liu J, Chen F*, He S*. Mineralized Enzyme-Based Biomaterials with Superior Bioactivities for Bone Regeneration. ACS Appl Mater Interfaces. 2022 Aug 17;14(32):36315-36330.

5.Zhou X, Cornel EJ, Fan Z*, He S*, Du J*. Bone-Targeting Polymer Vesicles for Effective Therapy of Osteoporosis. Nano Lett. 2021 Oct 13;21(19):7998-8007.

6.Shi S, Kang XJ, Zhou Z, He ZM, Zheng S*, He SS*. Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpous. Arthritis Res Ther. 2022 May 23;24(1):119.

7.Li G, Fan ZK, Gu GF, Jia ZQ, Zhang QQ, Dai JY, He SS*. Epidural Spinal Cord Stimulation Promotes Motor Functional Recovery by Enhancing Oligodendrocyte Survival and Differentiation and by Protecting Myelin after Spinal Cord Injury in Rats. Neurosci Bull. 2020 Apr;36(4):372-384.

8.Liao L, Jiang H, Fan Y, Lu RS, Wei C, Takarada T, He S*, Chen D*. Runx2 is required for postnatal intervertebral disc tissue growth and development. J Cell Physiol. 2019 May;234(5):6679-6687.

9.Fan G*, Liu H, Wang D, Feng C, Li Y, Yin B, Zhou Z, Gu X, Zhang H, Lu Y, He S*. Deep learning-based lumbosacral reconstruction for difficulty prediction of percutaneous endoscopic transforaminal discectomy at L5/S1 level: A retrospective cohort study. Int J Surg. 2020 Oct; 82:162-169.

10.Yang S, Fan G, Feng C, Fan Y, Xu N, Zhou H, Wang C*, Liao X*, He S*. Novel Nomograms and Web-Based Tools Predicting Overall Survival and Cancer-specific Survival of Solitary Plasmacytoma of the Spine. Spine (Phila Pa 1976). 2023 Sep 1;48(17):1197-1207.

11.Wu X, Liu W, Xiao X, Fan Y, Gu G, Yu S, Yan H, Wang X, Li X, Zhao Y, Ni H, He S*. Comparison of the clinical outcomes of VBE-TLIF versus MIS-TLIF for single-level degenerative lumbar diseases. Eur Spine J. 2024 Mar;33(3):1120-1128.

12.Gong H, Fan Y, Zhao Y, Chen F, Chen J, Yan H, Gu G, Wang C, Ni H*, He S*. Minimally invasive transforaminal lumbar interbody fusion by a novel two-medium compatible bichannel endoscopy system, technique note and preliminary clinical results. Eur Spine J. 2023 Aug;32(8):2845-2852.

13.Yang S, Zhong S, Fan Y, Zhu Y, Xu N, Liao Y, Fan G*, Liao X*, He S*. Research hotspots and trends on spinal cord stimulation for pain treatment: a two-decade bibliometric analysis. Front Neurosci. 2023 May 25; 17:1158712.

14.Zhou Z, Ni HJ, Hu S, Fan YS, Wang CF, Chen X, Zhu YJ, Li G, Liu F, Feng CB, He SS*. Original Designed Uniportal-Bichannel Spinal Endoscopic System (UBiSES) for Foraminoplasty in Percutaneous Endoscopic Transforaminal Discectomy. Orthop Surg. 2021 Oct;13(7):1987-1999.

15.Shi S, Zhou Z, Liao JJ, Yang YH, Wu JS, Zheng S*, He SS*. The impact and distinction of ‘lipid healthy but obese’and’lipid abnormal but not obese’phenotypes on lumbar disc degeneration in Chinese. J Transl Med. 2020 May 26;18(1):211.