科研业绩
擅长各种颅内外动脉瘤、狭窄、畸形、动静脉瘘、脑梗塞、眩晕、晕厥、脊髓小脑共济失调、认知障碍、走步不稳、构音障碍、吞咽困难、Lewis-Sumner综合症、疼痛性疾病、症状性脑萎缩、自闭症谱系障碍等脑血管病或疑难杂症的治疗。
Proficient in the treatment of various intracranial and extracranial aneurysms, stenosis, malformations, arteriovenous fistulas, cerebral infarction, vertigo, syncope, cerebellar ataxia, cognitive disorders, unsteady gait, dysarthria, dysphagia, Lewis-Sumner syndrome, painful diseases, symptomatic cerebral atrophy, autism spectrum disorder, and other cerebrovascular diseases or complex conditions.
一、代表性SCI论文
1. Ma J, Liu Y, Zhao K (通讯作者). Microcephaly type 22 and autism spectrum disorder: A case report and review of literature. Dialogues Clin Neurosci 2024;26(1):24-27. IF=8.3
Yang Y, Li J, Xiao Z, Yang X, Wang L, Duan Y, Zhao K(共同通讯作者), Liu A: Relationship between stress hyperglycemia ratio and prognosis in patients with aneurysmal subarachnoid hemorrhage: a two-center retrospective study. Neurosurgical review 2024, 47(1):315. IF=2.8
3.Wang JB, Junmiao Zhao JM , …, Zhao KJ(通讯作者). Anoikis-related gene signature associates with the immune infiltration and predicts the prognosis of glioma patients,Genes &disease, Available online 4 June 2024, 101346 IF=6.7996
4. Liu Y, Zhao S, Chen Y, Zhao KJ(通讯作者). Vimentin promotes glioma progression and maintains glioma cell resistance to oxidative phosphorylation inhibition. Cell Oncol (Dordr) 2023;46:1791-1806. IF=6.593
5. Liu Y, Lu S, Sun Y, Zhao KJ(通讯作者)et al. Deciphering the role of QPCTL in glioma progression and cancer immunotherapy. Front Immunol 2023;14:1166377.
IF=7.293
6. Liu Y, Chen Y, Wang F, Zhao KJ(通讯作者). Caveolin-1 promotes glioma progression and maintains its mitochondrial inhibition resistance. Discov Oncol 2023;14:161. IF=2.7
7. Zhao K, Zhao R, Yang X, et al. Predictors of unfavorable outcome in stent-assisted coiling for symptomatic unruptured intracranial spontaneous vertebral artery dissecting aneurysms (uis-VADAs): results from a multicenter study. J Neurointerv Surg 2021;14:1008-1013. IF=8.572
8. Zhao WY, Zhao KJ(共同第一), Huang QH, Xu Y, Hong B, Liu JM. Single-stage endovascular treatment of subarachnoid hemorrhage related to bilateral vertebral artery dissecting aneurysms[J]. Interventional neuroradiology: journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences,2016, 22 (2): 138-142.
IF:0.739 9. Yang P, Zhao K, Zhou Y, et al. Stent-assisted Coil Placement for the Treatment of 211 Acutely Ruptured Wide-necked Intracranial Aneurysms: A Single-Center 11-Year Experience. Radiology. 2015 Aug;276(2):545-52 IF:5.787
10. Fang YB, Zhao KJ (共同第一), Wu YN, et. al. Treatment of ruptured vertebral artery dissecting aneurysms distal to the posterior inferior cerebellar artery: stenting or trapping?. Cardiovasc Intervent Radiol. 2015;38(3):592-9. IF:2.144
11. Zhao KJ, Zhao R, Huang QH, et al. The interaction between stent(s) implantation, PICA involvement, and immediate occlusion degree affect symptomatic intracranial spontaneous vertebral artery dissection aneurysm (sis-VADA) recurrence after reconstructive treatment with stent(s)-assisted coiling. Eur Radiol. Sep 2014;24(9):2088-2096. IF: 4.014
12. Zhao KJ, Zhang YW, Xu Y, et al. Reconstruction of saccular and dissected intracranial aneurysms using Solitaire AB stents. PLOS One. 2013;8(2):e57253.
IF: 3.534
13. Zhao KJ, Fang YB, Huang QH, et al. Reconstructive Treatment of Ruptured Intracranial Spontaneous Vertebral Artery Dissection Aneurysms: Long-Term Results and Predictors of Unfavorable Outcomes. PLOS One. 2013;8(6): e67169. IF:3.534
14. Yan J, Zhao K(共同第一), Sun J, et al. Comparison between the formula 1/2ABC and 2/3Sh in intracerebral parenchyma hemorrhage. Neurological research. May 2013;35(4):382-388. IF: 1.449
15. Zhang HF, Zhao KJ (共同第一), Xu Y, et al. Lysyl oxidase polymorphisms and ischemic stroke--a case control study. Mol Biol Rep. Oct 2012;39(10):9391-9397.
IF: 2.506
16. Xu YZ, Zhao KJ (共同第一), Yang ZG, et al. Decreased plasma decorin levels following acute ischemic stroke: correlation with MMP-2 and differential expression in TOAST subtypes. Mol Med Rep. Dec 2012;6(6):1319-1324. IF: 1.17
17. Zhao KJ, Yang PF, Huang QH, et al. Y-configuration stent placement (crossing an kissing) for endovascular treatment of wide-neck cerebral aneurysms located at 4 different bifurcation sites. AJNR. American journal of neuroradiology. Aug 2012;33(7):1310-1316.
IF: 3.167
18. Zhang HF, Zhao KJ (共同第一), Yang PF, et al. Association between fibroblast growth factor receptor 4 Gly388Arg polymorphism and ischemic stroke. J Int Med Res. 2012;40(5):1708-1714. IF:0.958
19. Zhao KJ, Zhang RY, Sun QF, et al. Comparisons of 2/3Sh estimation technique to computer-assisted planimetric analysis in epidural, subdural and intracerebral hematomas. Neurological research. Nov 2010;32(9):910-917. IF: 1.439
20. Zhao KJ, Liu Y, Zhang RY, Wang XQ, Gao C, Shen JK. A precise, simple, convenient and new method for estimation of intracranial hematoma volume--the formula 2/3Sh. Neurological research. Dec 2009;31(10):1031-1036. IF: 1.439
21. Zhang RY, Zhao KJ, Tang YQ, Li L. Effect of isoflavone extracts from glycine max on human endothelial cell damage and on nitric oxide production. Menopause.2010;17:441-442. IF:3.141
22. Zhang RY, Cui W, Zhao KJ, et al. Validating sampling methods for measurement of circulating matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1. Pancreas, 2010;39(6):937-938. IF:3.008
二、代表性中文论文
1. 赵开军,王杰军,方亦斌,李佑祥,黄清海,赵瑞,杨新健,刘建民.支架重建技术治疗未破裂颅内自发性椎动脉夹层动脉瘤的预后及其影响因素[J].中华神经外科杂志,2018,34(8): 773-777.
2. 赵开军,杨鹏飞,黄清海等.Y型支架技术治疗颅内动脉分叉部宽颈动脉瘤[J].中国临床神经外科杂志.2013.18(6):321-324.
3. 赵开军,沈建康. 颅内血肿体积评估方法的影像和临床进展[J],中华神经外科疾病研究杂志,2010,9: 376-378.
4. 赵开军, 沈建康. 颅内血肿体积评估方法的影像和临床进展[J]. 中华神经外科疾病研究杂志, 2010, 9 : 376-378.
5. 赵开军, 沈建康. 胃泌素释放肽受体在肿瘤治疗中的研究进展[J]. 世界华人消化杂志, 2009, 17 (1): 63-67.
6. 赵开军,沈建康,孙青芳.胃泌素释放肽受体在肿瘤中分布的临床意义[J]. 国际肿瘤学杂志, 2008, 35 (9)
7. 赵开军, 任光阳. 极限法在颅内血肿体积计算中的应用[J]. 中华神经外科杂志, 2007, 23 (005): 363-363.
8. 赵开军, 任光阳. Chiari 畸形脊髓空洞症发病机制的力学探讨[J]. 中华神经外科杂志, 2006, 22: 642-644.
三、现阶段主持中的课题 (在研科研经费:80万)
1. 浦东新区卫生健康委员会,面上项目,远侧桡动脉入路在脑血管疾病诊疗中的安全性和推广应用研究,主持:10万,2023.01.01-2025.12.31
2.北京医学奖励基金会,神经科学创新发展研究项目,YXJL-2022-00351-0183,远桡或传统桡动脉入路诊疗症状性脑血管病致围手术期桡动脉闭塞的风险分析:一项前瞻性、单中心、随机、对照研究,2022.08.01-2025.08.01,在研,主持,30万;
3、上海市东方医院,引进人才启动基金,30万;
4.军队,“234学科攀峰计划”,2019YXK030,未破裂的椎基底动脉夹层(VBD)重建性治疗大数据分析及前瞻性研究,2020-01至2023-12,在研,主持,10万;
5.军队,长海医院教学研究与改革项目,CHJG2019036,借助3D图像和视频巧学动脉瘤微导管的塑形技术,2020-01至2020-12,在研,主持。
四、参编/参译专著
1.赵开军(参译).颅内动脉瘤的血流导向介入治疗(国家重点研发计划专项,2016YFC1300700)
2. 赵开军.椎动脉与椎基底动脉结合部夹层动脉瘤的治疗(第二篇/第三章).脑防委介入治疗适宜技术
3. 赵开军.颅内动脉瘤部分.脑血管病介入治疗操作规范
4. 赵开军,赵文元,第十七章:夹层动脉瘤;书名:颅内动脉瘤介入治疗学--基于病例的研究, 第二军医大学出版社, 8914, 2016.10.0
5. 赵开军,赵文元,第十一章:基底动脉尖动脉瘤;书名:颅内动脉瘤介入治疗学--基于病例的研究, 第二军医大学出版社, 5687, 2016.10.0
6.赵开军,脑卒中介入治疗.2022年