同济大学附属东方医院生殖中心主任;
Director of Reproductive Center, East Hospital Affiliated to Tongji University
中国医师协会生殖医学专业委员会第一届委员会生殖外科学组委员;
Member of the Reproductive Surgery Group of the first Committee of the Reproductive Medicine Professional Committee of the Chinese Medical Doctor Association
中国康复医学会生殖健康专业委员会第一届委员;
Member of the first Reproductive Health Professional Committee of Chinese Rehabilitation Medical Association
上海市医学会生殖医学委员;
Member of Reproductive Medicine Committee, Shanghai Medical Association
上海市医师协会生殖医学专业委员会第二届委员;
Member of the second Reproductive Medicine Professional Committee of Shanghai Medical Doctor Association
中国女医师协会生殖医学专业委员会委员;
Member of Reproductive Medicine Professional Committee of Chinese Women Medical Association
上海市生殖免疫专委会委员。
Member of Shanghai Reproductive Immunization Committee
主持国自然面上项目1项、中国人口与发展研究中心子课题1项、省部级科研课题2项;获省级科技进步二等奖2项、市级科技进步三等奖1项;发表SCI论文40余篇;获授权专利3项。
As the project initiator, guide over 4 scientific research projects, including one project of the National Natural Science Foundation, one subproject of China Population and Development Research Center and two projects at the provincial and ministerial level; Won 2 second prize of provincial science and technology progress and 1 third prize of municipal science and technology progress; Published more than 40 SCI papers; Have 3 authorized patents.
代表性论文:
Representative publications:
Tie1 contributes to the development of ovarian hyperstimulation syndrome under the regulation of EGR1 in granulosa cells. Exp Mol Med. 2022 Jan;54(1):81-90. doi: 10.1038/s12276-021-00722-8. Epub 2022 Jan 25. PMID: 35079118.
Circadian Clock Genes REV-ERBs Inhibits Granulosa Cells Apoptosis by Regulating Mitochondrial Biogenesis and Autophagy in Polycystic Ovary Syndrome. Front Cell Dev Biol. 2021 Aug 5;9:658112. doi: 10.3389/fcell.2021.658112. PMID: 34422794.
The E3 Ubiquitin Ligase SYVN1 Plays an Antiapoptotic Role in Polycystic Ovary Syndrome by Regulating Mitochondrial Fission. Oxid Med Cell Longev. 2022 Sep 19;2022:3639302. doi: 10.1155/2022/3639302. PMID: 36193086.
WEE1 promotes endometriosis via the Wnt/β-catenin signaling pathway. Reprod Biol Endocrinol. 2021 Oct 22;19(1):161. doi: 10.1186/s12958-021-00844-8. PMID: 34686198.
A novel homozygous variant in NLRP5 is associate with human early embryonic arrest in a consanguineous Chinese family. Clin Genet. 2020 Jul;98(1):69-73. doi: 10.1111/cge.13744. Epub 2020 Apr 16. PMID: 32222962.
Progestin-primed milder stimulation with clomiphene citrate yields fewer oocytes and suboptimal pregnancy outcomes compared with the standard progestin-primed ovarian stimulation in infertile women with polycystic ovarian syndrome. Reprod Biol Endocrinol. 2018 May 28;16(1):53. doi: 10.1186/s12958-018-0373-7. PMID: 29807533.
HOXA10 Expressing UCMSCs Transplantation Improved Endometrial Receptivity on Endometrial Injury. Curr Stem Cell Res Ther. 2023;18(7):1001-1012. doi: 10.2174/1574888X17666220919111814. PMID: 36121094.