(一) 主持的科研项目:
1.国家自然科学基金面上项目,81971384,蜕膜巨噬细胞中GPR133基因表达异常在复发性流产发生中的作用及机制研究,2020/01-2023/12,55万,在研,主持;
2.国家自然科学基金青年项目,81501270,赖氨酰氧化酶在子痫前期发生发展中的作用及其机制研究,2016/01-2018/12,18万,结题,主持;
3.同济大学青年优秀人才培养行动计划,1515219025,胎膜早破样本中LOX活性异常的分子机理研究,2015/01-2016/12,10万元,结题,主持
(二) 发表文章:
1.Xu XH#, Jia Y, Zhou X, Xie D, Huang X, Jia L, Zhou Q, Zheng Q, Zhou X, Wang K*, Jin LP*. Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating TGF-β/collagen pathway in preeclampsia. Exp Mol Med. 2019, 51 (2): 20;
2.Xu XH#, Bao Y#, Wang X, Yan F, Guo S, Ma Y, Xu D, Jin L, Xu J*, Wang J*. Hypoxic-stabilized EPAS1 proteins transactivate DNMT1 and cause promoter hypermethylation and transcription inhibition of EPAS1 in non-small cell lung cancer. FASEB J. 2018; 12, 32(12): 6694~6705;
3.Xu XH#, Huang XW#, Qun L, Li YN, Wang Y, Liu C, Ma YY, Liu QM, Sun K, Qian F, Jin L*, Wang JC*. Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans. Sci Rep-UK. 2014; 4:7465;
4.Xu XH#, Dong SS, Guo Y, Yang TL, Lei SF, Papasian CJ, Zhao M, Deng HW*. Molecular genetics studies of gene identification for osteoporosis: the 2009 update. Endocr Rev. 2010; 31(4):447-505;
5.Xu XH#, Xiong DH, Liu XG, Guo Y, Chen Y, Zhao J, Recker RR, Deng HW*. Association analyses of vitamin D-binding protein gene with compression strength index variation in Caucasian nuclear families. Osteoporos Int. 2010; 21(1): 99-107;
6.Yao Y#, Hao F, Tang LC, Xu XH* (并列通讯), Jin L*. Downregulation of HDAC8 expression decreases CD163 levels and promotes the apoptosis of macrophages by activating the ERK signaling pathway in recurrent spontaneous miscarriage. Mol Hum Reprod. 2020 Jul 1;26(7):521-531;
7.Tang LC#, Xu XH* (并列通讯), Jin L*. Molecular characteristics and possible function of innate lymphoid cells under different tissue conditions. Cytokine and Growth Factor Reviews. 2020 52:15-24;
8.Yao Y#, Xu XH* (并列通讯), Jin L*. Macrophage Polarization in Physiological and Pathological Pregnancy. Frontiers in Immunology. 2019 10:792;
9.Fan DX, Zhou WJ, Jin LP, Li MQ, Xu XH* (并列通讯), Xu CJ*. Trophoblast-Derived CXCL16 Decreased Granzyme B Production of Decidual γδ T Cells and Promoted Bcl-xL Expression of Trophoblasts. Reprod Sci. 2019 Apr; 26(4):532-542.