【近五年主持课题】
1、2024年浦东新区妇产科医疗联合体项目. 复发性流产合并抗磷脂综合征的规范化诊治.在研.
2、2024年【在肥胖多囊卵巢综合征受试者中评估HRS9531注射液的有效性和安全性的多中心、随机、双盲、安慰剂平行对照II期临床研究（方案编号：HRS9531-207）】.在研.
3、2023年上海市自然科学基金.CD24+蜕膜基质细胞在复发性流产中的作用和机制研究. No:23ZR1450100.在研.
4、2023年孕早期无创胎儿染色体非整倍体和微缺失/微重复检测技术开发. 横向课题.在研.
【近五年发表】
1. Zhu X, Wang Q, Lang J, Zhi Y, Fu Y, Bao S*. Role of follicle-stimulating hormone receptor polymorphism in predicting ovarian response to letrozole in women with polycystic ovary syndrome during ovulation induction. Front Endocrinol (Lausanne). 2025 Jun 19;16:1585655. doi: 10.3389/fendo.2025.1585655. PMID: 40612432; PMCID: PMC12221892.
2. Du M, Yang X, Zhang R, Yu N, Peng L, Lin J, Yan X, Wu Y, Bao S*. A relative-independent haplotype derivation method applied for noninvasive prenatal testing for chromosomal rearrangements in a pregnant carrier. Mol Genet Genomics. 2025 Feb 10;300(1):19. doi: 10.1007/s00438-025-02225-x. PMID: 39928155.
3. Li G, Du M, Deng X, Wang S, Zhou Z, Zhang J, Bao S*. Novel A4GALT Variants Cause Rare p Phenotype and Recurrent Pregnancy Loss in a Chinese Individual. Am J Med Genet A. 2025 Jun;197(6):e64017. doi: 10.1002/ajmg.a.64017. Epub 2025 Feb 5. PMID: 39907038.
4. Deng X, Qin D, Ding Q, Peng L, Li G, Bao S*. Vitamin B12 is correlated with insulin resistance and metabolism disorder markers in women with recurrent pregnancy loss. J Gynecol Obstet Hum Reprod. 2025 Jan;54(1):102864. doi: 10.1016/j.jogoh.2024.102864. Epub 2024 Oct 18. PMID: 39427844.
5. Qin D, Chen Z, Deng X, Liu X, Peng L, Li G, Liu Y, Zhu X, Ding Q, Zhang X, Bao S*.CD24+ decidual stromal cells: a novel heterogeneous population with impaired regulatory T cells induction and potential association with recurrent miscarriage. Fertil Steril. 2023 Nov 28:S0015-0282(23)02020-4. doi: 10.1016/j.fertnstert.2023.11.025.（IF 6.7，通讯作者）
6. Zhang Z, Zhou H, Deng X, Zhang R, Qu R, Mu J, Liu R, Zeng Y, Chen B, Wang L, Sang Q, Bao S*. IQUB deficiency causes male infertility by affecting the activity of p-ERK1/2/RSPH3. Hum Reprod. 2023 Jan 5;38(1):168-179. doi: 10.1093/humrep/deac244.（IF 6.353，通讯作者）
7. Bao S*, Chen Z, Qin D, Xu H, Deng X, Zhang R, Ma J, Lu Z, Jiang S, Zhang X. Single-cell profiling reveals mechanisms of uncontrolled inflammation and glycolysis in decidual stromal cell subtypes in recurrent miscarriage. Hum Reprod. 2023 Jan 5;38(1):57-74. doi: 10.1093/humrep/deac240.（IF 6.353，通讯作者）
8. Yu N, Kwak-Kim J, Bao S*. Unexplained recurrent pregnancy loss: Novel causes and advanced treatment. J Reprod Immunol. 2023 Feb:155:103785. doi: 10.1016/j.jri.2022.103785.（IF 3.4，通讯作者）
9. Deng X, Sang Q, Zhang R, Mu J, Bao S*. The association of APOH and NCF1 polymorphisms on susceptibility to recurrent pregnancy loss in women with antiphospholipid syndrome. J Assist Reprod Genet. 2023 Jul;40(7):1703-1712. doi: 10.1007/s10815-023-02829-5.（IF 3.357，通讯作者）
10. Du M, Peng L, Zhang R, Bao S*. Successful pregnancy and delivery after premature ovarian insufficiency combined with undifferentiated connective tissue disease: a case report. Endocr Metab Immune Disord Drug Targets. 2023 Nov 3. doi: 10.2174/0118715303248685231023114212. （IF 1.9，通讯作者）
11. Dong J#, Jin L#, Bao S#, Chen B, Zeng Y, Luo Y, Du X, Sang Q, Wu T, Wang L.Ectopic expression of human TUBB8 leads to increased aneuploidy in mouse oocytes.Cell Discov. 2023 Oct 24;9(1):105. doi: 10.1038/s41421-023-00599-z. （IF 33.5 共第一）
12. Peng L, Yang W, Deng X, Bao S*. Research progress on ANXA5 in recurrent pregnancy loss. J Reprod Immunol. 2022 Sep;153:103679. doi: 10.1016/j.jri.2022.103679. Epub 2022 Jul 28. PMID: 35964539.
13. Qin D, Xu H, Chen Z, Deng X, Jiang S, Zhang X, Bao S*. The peripheral and decidual immune cell profiles in women with recurrent pregnancy loss. Front Immunol. 2022 Sep 13;13:994240. doi: 10.3389/fimmu.2022.994240. PMID: 36177021; PMCID: PMC9513186.
14. Li G, Ding Q, Deng X, Bao S*. Assessment of the Levels of Peripheral Lymphocytes Subpopulation in Healthy Women of Childbearing Age: a Prospective Cohort Study. Clin Lab. 2022 Apr 1;68(4).
15. Zhang R, Li G, Du M, Bao S*. Effect of Ezrin on regulating trophoblast cell invasion via PKC signaling pathway in unexplained recurrent spontaneous abortion. Reprod Biol. 2022 Mar 21;22(2):100634. doi: 10.1016/j.repbio.2022.100634. （IF:2.376）
16. Ao J, Huo X, Zhang J, Mao Y, Li G, Ye J, Shi Y, Jin F, Bao S*, Zhang J. Environmental exposure to bisphenol analogues and unexplained recurrent miscarriage: A case-control study. Environ Res. 2022 Mar;204(Pt C):112293. doi: 10.1016/j.envres.2021.112293. （IF:6.498）
17. Liu Y, Du M, Gan Y, Bao S, Feng L, Zhang J. Triglyceride Induced Metabolic Inflammation: Potential Connection of Insulin Resistance and Recurrent Pregnancy Loss. Front Endocrinol (Lausanne). 2021 Apr 15;12:621845. doi: 10.3389/fendo.2021.621845. （IF:5.555）
【参编专著】
1、实用妇产科学.人民卫生出版社. 第三版. 主编华克勤 丰有吉.
2.、自然流产.人民卫生出版社.第一版. 主编 林其德.
3、环境因素与不孕不育.湖北科技出版社.第一版 主编熊承良.
4、Recurrent Pregnancy Loss.中国科学技术出版社.第三版 主译 曹云霞.
5、B cell pathologyand repeated implantation failures. 主编：Kwak-Kim - Immunology of Recurrent Pregnancy Loss and Implantation Failure
6、生殖免疫问答与病例精选. 湖北科学技术出版社. 第一版 主编 张艳 鲍时华 吴琰婷 尹太郎.
【国家发明专利授权】
1、一种蜕膜和绒毛配对组织芯片、制备方法及其应用。授权日期2019年10月9日，专利号 201710598366.7
2、蜕膜和绒毛配对cDNA芯片。授权日期2020年09月01日，专利号：201710598345.5
【专利申请】
1、一种基于血清或血浆Activin A水平检测的自然流产风险预测方法；鲍时华，盛世乐.2025年
