近年作为负责人主持国家自然科学基金面上项目2项,主持浦东新区科委民生科研项目1项,以通讯作者发表SCI论文10余篇,代表性论文如下:
(1)Wang J, Xiu M, Wang J, Gao Y, Li Y(李砚东). METTL16-SENP3-LTF axis confers ferroptosis resistance and facilitates tumorigenesis in hepatocellular carcinoma.J Hematol Oncol.2024 Sep 2;17(1):78.
(2)Li L, Xie D, Yu S, Ma M, Fan K, Chen J, Xiu M, Xie K, Li Y(李砚东), Gao Y. WNK1 Interaction with KEAP1 Promotes NRF2 Stabilization to Enhance the Oxidative Stress Response in Hepatocellular Carcinoma. Cancer Res. 2024 Sep 4;84(17):2776-2791.
(3)Yu J, Xiu M, Yu S, Chen Z, Li Y(李砚东), Gao Y. The Role of CAF-derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression. Adv Sci (Weinh).2025 Jun 20:e05769.
(4)Yu J, Hu Q, Fan K, Gao Y, Li Y(李砚东). C15orf39, a downstream effector of PI3K/AKT signaling, promotes gastric carcinogenesis and correlates with patient outcomes.Int J Biol Macromol. 2025 May;306(Pt 3):141615.
(5)Gao X, Bao W, Bai J, Fan K, Li L, Li Y(李砚东). UHMK1 aids colorectal cancer cell proliferation and chemoresistance through augmenting IL-6/STAT3 signaling. Cell Death Dis, 2022 May 2;13(5):424.
(6)Li L, Yu S, Chen J, Quan M, Gao Y, Li Y(李砚东). miR-15a and miR-20b sensitize hepatocellular carcinoma cells to sorafenib through repressing CDC37L1 and consequent PPIA downregulation. Cell Death Discov. 2022 Jun 27;8(1):297.