同济的学附属同济医院肿瘤内科 科主任
Chief
of Department of Ocology of Tongji Hospital
Affilated Tongji University
中国医师协会结直肠肿瘤内科专业委员会委员
Committee
of Internal Medcine section of Colorectal Oncology branch of Chinese Physician's
Association
上海市浦东新区肿瘤专业委员会委员
Member
of Oncology Specialized Committee of Pudong New Area, Shanghai
2000-2003
主要研究激活素A与肝纤维化的关系,探讨激活素A促进肝纤维化发生发展的机制,并检测肝硬化患者血清与腹水激活素A水平,提示其水平的变化与肝硬化相关,是一项鉴别良恶性腹水的潜在标记物。
2000-2003
Research
on the relationship between activin A and hepatic fibrosis. Based on the assay
of serum and ascites activin A in patients with hepatic cirrhosis, discussed
the role of activin A in the occurrence and development of hepatic fibrosis,
suggesting the correlation between the level of activin A and hepatic
cirrhosis, indicating that activin A maybe a potential biomarker for benign and
malignant ascites.
2005-2008
进行临床试验,探讨同步放化疗在胃癌辅助治疗中的作用,证实同步放化疗减少T3-4胃癌患者术后局部复发率,延长PFS。
2005-2008
Clinical
trials on the role of concurrent chemoradiotherapy in adjuvant treatment of
gastric cancer, proved that concurrent chemoradiotherapy reduced the local
recurrence rate and prolonged PFS in T3-4 gastric cancer patients.
2009-2014
糖组学在胰腺癌诊治中的应用研究。N-糖链在胰腺癌患者血清中的水平反映病情的变化,通过分析N-糖链不同成分的变化,探讨N-糖链作为胰腺癌早期诊断指标的可能性。
2009-2014
Application
of glycomics in the
diagnosis and treatment of pancreatic caner. The serum level of N-glycan in
pancreatic cancer patient correlates with the variation of disease stage. Based
on the assay of different components of N-glycan, explore the possibility of
N-glycan as an diagnostic biomarker in early stage,
2012-2014
个体化诊断技术在结直肠癌患者诊治中的作用。通过基于基因检测基础上的个体化治疗,提高肿瘤治疗缓解率,降低毒副反应,建立结直肠癌精准治疗的理念。
2012-2014
Individual
therapy in the diagnosis and treatment of colorectal cancer. Individual therapy
based on gene detection improves the remission rate of tumor and reduces
tocicity, establishing the concept of precise treatment for colorectal cancer.
2018-2020
获得市卫计委基金资助,主要研究外泌体FRLnc1作为胃癌早期诊断、疗效判断及预后分析的分子标志物。
2018-2020
Supported
by Shanghai Municipal Commission of Health and Family Planning, explore he role
of exosome FRLnc1 as an biomarker in the early diagnosis, efficacy evaluation
and prognosis of gastric cancer.
在各类期刊共发表文章20余篇,其中SCI收录7篇。
承担省部级及市级课题各一项,参与各级课题多项。
Published
more than 20 articles in different journals, including 7 indexed by SCI.
In
charge of two projects supported by provincial and municipal, respectively.
Participation in many projects at all levels.