上海市第十人民医院病理科带组组长，生物样本库负责人，上海市医师协会病理专委会青年委员，上海研究型医院学会临床转化CBDTM专业委员会委员，中国生物医药协会组织样本库分会青年工作组成员，Journal of Translational Medicine青年编委，国家科技重大项目评审专家，国家自然科学基金评审专家。
Lead of the Pathology Group, Department of Pathology；Shanghai Tenth People's Hospital；Director of the Biobank；Young Member, Pathology Professional Committee, Shanghai Medical Doctor Association；Member, Clinical Translation CBDTM Professional Committee, Shanghai Society of Research Hospitals；Member, Youth Working Group, Tissue Bank Branch, China Association for Biomedical Industry and Technology；Young Editorial Board Member, Journal of Translational Medicine；Review Expert for National Major Science and Technology Projects；Review Expert for National Natural Science Foundation of China.
先后主持国家自然科学基金和上海市自然基金等课题，在相关领域发表SCI论文31篇，其中以第一作者或通讯作者在Signal Transduction Targeted Therpy、Nature communications等杂志上发表14篇论文。
I have successively presided over projects such as the National Natural Science Foundation of China and the Shanghai Natural Science Foundation, and has published 31 SCI papers in relevant fields. Among them, 14 papers were published as the first author or corresponding author in journals including Signal Transduction and Targeted Therapy and Nature Communications.
【代表性研究成果（Representative papers）】
1. Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer. Sig Transduct Target Ther 6, 398 (2021).
2. Profiling Fusobacterium infection at high taxonomic resolution reveals lineage-specific correlations in colorectal cancer. Nat Commun. 2022 Jun 9;13(1):3336.
3. Targeting integrin α5 in fibroblasts potentiates colorectal cancer response to PD-L1 blockade by affecting extracellular-matrix deposition. J Immunother Cancer. 2023 Dec 1;11(12):e007447.
4. Detection of tissue colonizing bacteria and their association with clinicopathological and molecular features of inflammatory bowel disease. J Transl Med. 2025 Oct 15;23(1):1107.
5. Integrin alpha5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic marker, Mol Oncol, 13 (2019) 2697-2714.
6. VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2. Nature communications 8 （2017）, 15337.
