主持国家自然基金青年项目一项(No. 81302110)、上海市自然科学基金面上项目一项(No. 19ZR1447100)、参与多项国家自然基金和省部级课题。以第一或并列第一作者发表SCI论文10余篇,累计影响因子>30分,单篇最高被引18次。
National
Natural Science Foundation of China (No. 81302110), ¥23,000 “The important role
played by DEPTOR-mTOR signaling pathway in colitis associated colorectal cancer
and the therapeutic mechanisms of glutamin” Yun Tian (PI);Natural Science Foundation
of Shanghai (No. 19ZR1447100), ¥20,000 “Effect and mechanism of intestinal flora on immune
response in mice with colorectal cancer” Yun Tian (PI)
[1]
Yun Tian, Hamzah Abu-Sbeih, and Yinghong Wang. Immune Checkpoint
Inhibitors-Induced Hepatitis , Advances in Experimental Medicine.
2018;995:159-164. (IF 2.126)
[2]Yun
Tian, Hamzah Abu-Sbeih, and Yinghong Wang. Immune Checkpoint
Inhibitors-Induced Colitis. Advances in Experimental Medicine.
2018;995:151-157. (IF 2.126)
[3]
Yun Tian, Qing Xu, Liqun Sun, Ying Ye, Guozhong Ji. Short-chain fatty
acids administration is protective in colitis-associated colorectal cancer
development. J Nutr Biochem. 2018 Jul;57:103-109. (IF 4.5)
[4] Jie Ding, Juan Li, HaiYan Wang, Yun Tian, Min Xie, XueZhi
He, Hao Ji, Zhonghua Ma, Bingqing Hui, Keming Wang, and Guozhong Ji. Long noncoding RNA CRNDE
promotes colorectal cancer cell proliferation via epigenetically silencing
DUSP5/CDKN1A expression. Cell Death and Disease (2017) 8, e2997. (IF 5.638 并列第一作者)
[5]
Yun Tian, Keming Wang, Yingrui Fan, et al. Chemopreventive Effect of
Dietary Glutamineon Colitis-Associated Colorectal Cancer Is Associated with
Modulation of the DEPTOR/mTOR Signaling Pathway. Nutrients. 2016 May 2;8(5).
pii: E261. (IF 3.27)
[6]
Yi Li, Yun Tian, Weiming Zhu, et al. IL-10/microRNA-155/SHIP-1 signaling
pathway is crucial for commensal bacteria induced spontaneous colitis,
Biochemical Pharmacology, 2016.9.15,116:100-106 (IF 5.091 并列第一作者)
[7]
Yun Tian, Keming Wang, Juan Li, et al. The association between serum
lipids and colorectal neoplasm: a systemic review and meta-analysis. Public
Health Nutr. 2015 Mar 17:1-16. (IF 2.483)
[8]
Yun Tian, Jirong Wang, Ying Ye, et al. Apolipoprotein E Polymorphism and
Colorectal Neoplasm: Results from a Meta-Analysis. Plos One. 2014 Jul
16;9(7):e102477. (IF 3.534)
[9]
Yi Li, Yun Tian, Weiming Zhu, et al. Cesarean delivery and risk of
inflammatory bowel disease: a systematic review and meta-analysis. Scandinavian
Journal of Gastroenterology. 2014,49(7):834-44. (IF 2.329 并列第一作者)
[10]
Yun Tian, Keming Wang, Zhaoxia Wang, et al. Chemopreventive effect of
dietary glutamine on colitis-associated colon tumorigenesis in mice.
Carcinogenesis, 2013, 34(7): 1593-1600. (IF 5.266)
[11]
Yi Li, Yun Tian, Weiming Zhu, et al. Triptolide induces suppressor of
cytokine signaling-3 expression and promotes lamina propria mononuclear cells
apoptosis in Crohn's colitis. International Immunopharmacology, 2013,16:
268-274.(IF 2.711 并列第一作者)
[12]
Yun Tian, Ying Ye, Wei Gao, et al. Aspirin promotes apoptosis in a
murine model of colorectal cancer by mechanisms involving down-regulation of
IL-6-STAT3 signaling pathway. International Journal of Colorectal Disease,
2011, 26:13-22. (IF 2.415)
[13]
Yun Tian, Yi Li, Zhenhua Hu, et al. Differential effects of NOD2
polymorphisms on colorectal cancer risk: a meta-analysis. International Journal
of Colorectal Disease, 2010,25:161-168. (IF 2.415)
会议论文
[1]
Yun Tian, et al. Extracellular Vesicles Derived from HT-29 Colorectal Cancer
Cells Induce Endothelial Cell Activation and Procoagulant Activity.
Blood(IF11.841). 2015 Dec 3; 126 (23) 3456-3456.
[2]
Yun Tian, et al. Short-chain fatty acidsadministration is protective in
colitis-associated colorectal cancerdevelopment(P112), the 12th Congress of
ECCO – Inflammatory Bowel Diseases, Journal of Crohn’s and Colitis(IF6.585).
2017 Feb.
[3]
Yun Tian, et al. Faecalibacterium prausnitzii prevents tumorigenesis in a model
of colitis-associated colorectal cancer (DDW 2017 Abstract # 2643958),
Gastroenterology(IF 18.187). 2017 May.