一、发表文章(Publications)
Lijun Liao, Kai Markus Schneider, Mick Frissen, Till Strowig, Hanns-Ulrich Marschall, Huan Su, Daniela Kroy, Annika Wahlström, Eric J.C. Galvez, Antje Mohs, Jin Peng, Julia Jung, Johanna Reißing, Alexander Wree, Henning Wolfgang Zimmermann, Veerle Bieghs, Thomas Longerich, Christian Liedtke, Francisco Javier Cubero, Christian Trautwein. Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis. Gut. 2019 Aug;68(8):1477-1492. (IF=31.973)
Francisco Javier Cubero*, Jin Peng*, Lijun Liao*, Huan Su, Gang Zhao, Miguel Eugenio Zoubek, Ricardo Macias-Rodriguez, Astrid Ruiz-Margain, Johanna Reißing, Henning W. Zimmermann, Nikolaus Gassler, Tom Luedde, Christian Liedtke, Maximilian Hatting, Christian Trautwein. Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis. J Hepatol. 2018 Dec;69(6):1326-1334. (* 共同第一作者,Co-first author,IF=30.083)
Junyi Duan, Xin Chen, Jing Li, Yi Gao, Yixing Wang, Gang Zhao, Yuelai Chen, Lijun Liao. Acupoint catgut embedding as adjunctive therapy for patients with gallstones. Journal of Clinical Gastroenterology. 2021 Jan 19. doi: 10.1097/MCG.0000000000001487. Epub ahead of print. PMID: 33471487. (Corresponding authors,IF=3.186)
Weizhi He, Kai Jiang, Hua Qiu, Lijun Liao#, Shasha Wang. 16-membered ring macrolides and erythromycin induce ermB expression by different mechanisms. BMC Microbiol 22, 152 (2022). https://doi.org/10.1186/s12866-022-02565-3(#共同通讯作者,IF=4.465)
Mick Frissen, Lijun Liao, Kai Schneider, Sonja Djudjaj, Philip Puchas, Johannes Haybaeck, Alexander Wree, Ulrike Rolle-Kampczyk, Martin von Bergen, Eicke Latz, Peter Boor and Christian Trautwein. Bidirectional role of NLRP3 during acute and chronic cholestatic liver injury. Hepatology. 2020,73(5):1836-1854. doi: 10.1002/hep.31494 (IF=17.425)
Kai Markus Schneider, Carsten Elfers, Ahmed Ghallab, Carolin Victoria Schneider, Eric J C Galvez, Antje Mohs, Konrad Kilic, Lijun Liao, Anika Nier, Eicke Latz, Ina Bergheim, Christoph A Thaiss, Jan G Hengstler, Till Strowig, Christian Trautwein. Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury. Cell Mol Gastroenterol Hepatol. 2021;11(4):909-933. doi: 10.1016/j.jcmgh.2020.11.002. (IF=9.225)
Kai Markus Schneider, Lena Susanna Candels, Johannes R Hov, Maiju Myllys, Reham Hassan, Antje Mohs, Sebastian Zühlke, Lijun Liao, Carsten Elfers, Konrad Kilic, Marcus Henricsson, Antonio Molinaro, Maximilian Hatting, Ayham Zaza, Dirk Drasdo, Mick Frissen, Jan G Hengstler, Hanns-Ulrich Marschall, Ahmed Ghallab, Christian Trautwein. Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling. Nat Metab. 2021 Sep;3(9):1228-1241. doi: 10.1038/s42255-021-00452-1. (IF=19.865)
Kai Markus Schneider, Veerle Bieghs, Felix Heymann, Wei Hu, Daniela Dreymueller, Lijun Liao, Mick Frissen, Andreas Ludwig, Nikolaus Gassler, Oliver Pabst, Eicke Latz, Gernot Sellge, John Penders, Frank Tacke, and Christian Trautwein*, CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis. Hepatology. 2015, 62(5):1405–1416. (IF=17.425)
Fengjie Hao, Francisco Javier Cubero, Pierluigi Ramadori, Lijun Liao, Ute Haas, Daniela Lambertz, Roland Sonntag, Jörg- Martin Bangen, Nikolaus Gassler, Mareike Hoss, Konrad L Streetz, Johanna Reissing, Henning W Zimmermann, Christian Trautwein, Christian Liedtke and Yulia A Nevzorova*,Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice. Cell Death and Disease. Nature Publishing Group; 2017,8 (10): e3152. (IF=10.717)
二、主持的基金(Findings)
1. 国家自然科学基金 面上项目,81971814,回肠FXR-FGF19/15信号通路在脓毒症胆汁淤积性肝损伤中的调控机制研究,2020.01-2023.12。主持。
National Natural Science Foundation of China, General Program, 81971814,The mechanism of ileum FXR-FGF19/15 signaling pathway in sepsis associated cholestasis liver injury. 2020.01-2023.12. Project leader.
2. 上海市浦江人才计划,2020PJD050,肠道MyD88促脓毒症肠-肝轴紊乱的病理机制研究,2020.11-2022.10,主持。
Shanghai Pujiang Program,2020PJD050,Pathological mechanism of gut-liver axis disorder in intestinal MyD88 aggravating sepsis, 2020.11-2022.10, Project leader.
3.上海市浦东新区卫生系统学科带头人培养计划,PWRd2020-06,脓毒症肠-肝轴紊乱的病理机制研究。2020.10-2024.09。主持。
Academic medicine leader