同济大学附属东方医院，麻醉科主任，规范化住院医师培训麻醉专业基地主任、麻醉教研室主任
中华医学会围术期器官保护及支持学组委员兼学术秘书
中华医学会麻醉学分会学科建设与管理学组委员
中国医师协会麻醉学医师分会骨科学组委员
中国心胸血管麻醉学会创新推广分会常委
中国心胸血管麻醉学会胸科麻醉分会常委
中国心胸血管麻醉学会疼痛治疗学分会常委
中国研究型医院学会麻醉学专业委员会委员
国家级、上海市住院医师规范化培训督导专家
中国医学模拟教学联盟理事
上海市医学会麻醉科分会委员兼疼痛学组组长
上海市医师协会麻醉科医师分会可视化麻醉工作组副组长
国家自然科学基金评审专家
Director of anesthetic department，Shanghai East Hospital, Tongji University
Member and Academic Secretary of the Perioperative Organ Protection Group in Chinese Society of Anesthesiology
Member of the Discipline construction Group in Chinese Society of Anesthesiology
member of Anesthesiology Branch of Chinese Medical Doctor Association
Standing Committee Member of Innovation and Promotion Branch，Chinese Society of Cardiothoracic and Vascular Anesthesiology
Standing Committee Member of Thoracic Anesthesia Branch, Chinese Society of Cardiothoracic and Vascular Anesthesiology
Standing Committee Member of Pain Therapy Branch, Chinese Society of Cardiothoracic and Vascular Anesthesiology
member of Anesthesiology Professional Committee of the Chinese Research Hospital Association
National and Shanghai resident standardized training supervision experts
Member of Chinese Medical Stimulation Teaching Alliance
deputy chief of pain management group in Anesthesiology Branch of Shanghai Medical Association
member of Anesthesiology Branch of Shanghai Medical Doctor Association
在大型三甲综合医院麻醉学领域从业25年，现任同济大学附属东方医院麻醉科主任、麻醉教研室主任、麻醉基地主任。主持国家自然科学基金项目3项，上海市浦江人才资助课题、上海市自然科学基金面上项目等在内的省部级及其他项目12项。目前在研经费超过200万。累计发表中英文论著50余篇，参编专著8部。入选上海市浦江人才计划、上海市浦东新区明珠领军人才计划、上海交通大学优秀教师出国进修计划等在内的人才计划5项；获得上海市住院医师规范化培训优秀带教老师、上海交通大学附属第一人民医院卓越医师、优秀青年医师、同济大学附属东方医院东方人物等荣誉称号。 2009年起先后受聘为上海交通大学硕士生导师、上海交通大学博士生导师、同济大学博士生导师、博士后合作导师及同济大学教授。培养研究生19人，多人获得上海交通大学杨帆计划、国家自然科学基金青年及面上项目、上海市优秀毕业生、上海交通大学优秀毕业生称号。长期聚焦麻醉与脑功能调控研究，围绕“围术期神经功能保护、认知功能障碍”开展基础和临床研究。
（一）代表性科研立项
国家自然基金委员会，面上项目， 82171183，“应激颗粒介导麻醉和手术促进阿尔茨海默病快速进展的机制研究”，2022-01至2025-12，55万元，在研
National Natural Science Foundation of China, General Program, 82171183, “Mechanisms of stress granules mediating anesthesia and surgery promoting the rapid progression of Alzheimer’s disease”, from 2022-01 to 2025-12, 550,000 yuan, in research
国家自然基金委员会，面上项目，81771269，“β-arrestin2在δ阿片受体激动剂抑制TLR4炎症通路减轻脑缺血再灌注损伤中的作用及机制研究”，2018.01至2021.12，54万元，结题。
National Natural Science Foundation of China, General Program, 81771269, “Effect and mechanism of β-arrestin2 on δ opioid receptor agonist DADLE regulating TLR4 pathway in cerebral ischemia-reperfusion injury”, from 2018.01 to 2021.12, 540,000yuan, complete
国家自然基金委员会，青年项目，30901392，“腹主动脉内局部灌注克伦特罗和丁氧胺调控β2 肾上腺素受体对脊髓缺血再灌注损伤保护作用及机制的研究”，2010.01至2012.12，20万元，结题。
National Natural Science Foundation of China, Youth Project, 30901392, “Research on the protective effect and mechanism of local perfusion of clenbuterol and butoxyamine in the abdominal aorta on β2-adrenergic receptors against spinal ischemia-reperfusion injury”, from 2010.01 to 2012.12, 200,000yuan, complete
上海市人力资源和社会保障局，上海市浦江人才计划资助课题，17PJD035，“Wnt /β-catenin/GSK3β信号通路受抑介导的Tau蛋白病变及炎症反应在AD患者麻醉手术后认知功能恶化中的作用”，2017.09至2019.09，20万元，结题。
Shanghai Municipal Human Resources and Social Security Bureau, Shanghai Pujiang Talent Program funded project, 17PJD035, “Role of Tau protein lesions mediated by inhibition of Wnt/β-catenin/GSK3β signaling pathway and inflammatory response in cognitive deterioration after anesthesia surgery in AD patients”, from 2017.09 to 2019.09, 200,000yuan, complete
（二）近五年发表代表性SCI论文
Yang Y,Yue Zhao,Jingyu Feng,Naqi Lian,Jiafeng Yu,Yongyan Yang,Junyan Yao*,Yonghao Yu. Repeated Exposure to Sevoflurane in Neonatal Mice Induces Cognitive and Synaptic Impairments in a TTLL6‐Mediated Tubulin Polyglutamylation Manner. CNS Neuroscience & Therapeutics . 2025; 31:e70376
Liu J, Li C, Yao J, Zhang L, Zhao X, Lv X, Liu Z, Miao C, Wang Y, Jiang H, Yu W, Wang T, Wang D, Wang E, Gu X, Dong H, Cao J, Shen Y, Song W, Chen S, Wang Y, Liu G, Xie Z, Xiong L, Zheng JC. Clinical biomarkers of perioperative neurocognitive disorder: initiation and recommendation. Sci China Life Sci. 2025 Jul;68(7):1912-1940.doi: 10.1007/s11427-024-2797-x.
Junyao Zhang, Yinglin Zhang, Yingying Zhang, Junyan Yao*. The Association of Brain Insulin Resistance with Anesthesia/Surgery-Induced Cognitive Deterioration Is Female-Specific in 5XFAD Transgenic Mice. Journal of Alzheimer’s Disease.
Zhang J, Wang Y, Zhang Y, Yao J*. Genome-wide association study in Alzheimer’s disease: a bibliometric and visualization analysis. Front Aging Neurosci. 2023;15:1290657. 2023；Nov 29. doi:10.3389/fnagi.2023.1290657
Zhang Junyao; Zhang Tong; Wang Yinuo; Yao Liangfang; Yao Junyan*. Gα13-mediated Signaling Cascade was related to the Anesthesia and Surgery caused tau Pathology in 5XFAD Transgenic Mice, Journal of Alzheimer’s disease :2023； 93(2),545-560.
Yingying Zhang , Junyao Zhang, Yinuo Wang, Junyan Yao*. Global trends and prospects about synaptic plasticity in Alzheimer’s disease: a bibliometric analysis. Front. Aging Neurosci., 2023 Sep 5:15:1234719. doi: 10.3389/fnagi.2023.1234719.
Yinuo Wang, Junyao Zhang, Yingying Zhang , Junyan Yao*. Bibliometric analysis of global research profile on ketogenic diet therapies in neurological diseases: Beneficial diet therapies deserve more attention. Frontiers in Endocrinology. DOI:10.3389/fendo.2022.1066785
Ying Zhao, Peng Pan, Yue Lei, Danyun Fu, Junyan Yao*. Ultrasound-guided transversus thoracic muscle plane-pectoral nerve block for postoperative analgesia after modified radical mastectomy: a comparison with thoracic paravertebral nerve block. Perioperative medicine.
Yang Shen, Tong Zhang, Yinglin Zhang, Yinuo Wang, Junyan Yao* Stress granules modulate SYK to cause tau-associated neurocognitive deterioration in 5XFAD mice after anesthesia and surgery. Frontiers in aging neuroscience. 2021,27;13:718701
Shen Yang, Li X, Yao Junyan*. Develop a clinical prediction model for postoperative cognitive dysfunction after major non-cardiac surgery in elderly patients: a protocol for a prospective observational study. Gerontology. 2021,(68):538-545
Tong Zhang, Yang Shen, Yiqing Guo, Junyan Yao* Identification of key transcriptome biomarkers based on a vital gene module associated with pathological changes in Alzheimer’s disease. Ageing,2021,13:14940-14967.
Fu Danyun, Liu Haitong, Zhujiang, Xu Hongjiao, Junyan Yao*. D-Ala2, D-Leu5] Enkephalin Inhibits TLR4/NF-κB Signaling Pathway and Protects Rat Brains against Focal Ischemia-Reperfusion Injury, Mediators of Inflammation, 2021,2021：6661620
Hua Liu, Xiaojian Weng, Junyan Yao, Jun Zheng, Xiang Lv, Xuhui Zhou, Hong Jiang, Shitong Li.Neuregulin-1β Protects the Rat Diaphragm during Sepsis against Oxidative Stress and Inflammation by Activating the PI3K/Akt Pathway. Oxidative Medicine and Cellular Longevity. 2020, 2020:1720961.
Linwen Liu, Yongfu Xu#, Yachun Zhou, Shitong Li, Junyan Yao*. Regionally infused Lidocaine can dose-dependently protect the ischemic spinal cord in rabbits and may be associated with the EAA Changes. Neuroscience Letters. 2020 Apr 23,725:134889.
（三）入选人才计划及荣誉
上海市浦江人才计划
上海市住院医师规范化培训优秀带教老师
上海市浦东新区明珠领军人才项目
上海市浦东新区领先人才项目
上海交通大学医学院中青年教师国外访学进修计划
上海交通大学附属第一人民医院卓越医师人才计划
上海交通大学附属第一人民医院优秀青年医学人才计划
上海市医师协会麻醉科医师分会-科普比赛（视频类）一等奖
同济大学附属东方医院“东方人物”
