Advanced materials for biomedical applications
 
Awards: 
2015    1000Plan Professorship for Young Talents by the Chinese Government
2015    Pujiang Talents by Shanghai Government
2014    Chicago Biomedical Consortium Postdoctoral Research Award
2014    The University of Chicago 21st Annual Charles B. Huggins Symposium, Oral Presentation Award
2012    University of Chicago Biological Sciences Division Postdoc Association, Travel Award
2010   239th National American Chemical Society Meeting in Physical Chemistry Division, Outstanding Student Poster Award
2010    239th National American Chemical Society Meeting in Colloid and Surface Chemistry Division, Best Student Oral Presentation at the Biofunctional Architectures Symposium Session
2010     American Chemical Society Meeting-in-Miniature, Graduate Student Awardee
2010     Research ShowCASE Graduate Student Poster Contest, 2nd Prize 
2009     The Microscopy Society of Northeastern Ohio Fall Meeting, 1st Place Graduate Physical Poster
2009     Research ShowCASE Graduate Student Poster Contest, 1st Prize 
2008     Research ShowCASE Graduate Student Poster Contest, 1st Prize 
2007     Research ShowCASE Graduate Student Poster Contest, Honorable Mention 
2004     Excellent Undergraduate Thesis of Hubei Province, P.R.China
2003     Excellent Student of Wuhan University, Wuhan University
2002     Excellent Student of Wuhan University, Wuhan University
2001     Excellent Student of Wuhan University, Wuhan University
                                                             
                                                  
                                                  
 1、Qishuai Feng, Yajing Shen, Yingjie Fu, Megan E. Muroski, Peng Zhang, Qiaoyue Wang, Chang Xu, Maciej S. Lesniak, Gang Li*, Yu Cheng*, “Self-Assembly of Gold Nanoparticles Shows Microenvironment-Mediated Dynamic Switching and Enhanced Brain Tumor Targeting”, Theranostics, 2017, 7(7), 1875-1889.(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479275/)
2、Yajing Shen, Congyu Wu, Taro Q. P. Uyeda, Gustavo R. Plaza*, Bin Liu, Yu Han, Maciej S. Lesniak, and Yu Cheng*, “Elongated Nanoparticle Aggregates in Cancer Cells for Mechanical Destruction with Low Frequency Rotating Magnetic Field”, Theranostics, 2017, 7(6), 1735-1748.(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436524/)
 
3、Yingjie Fu, Qishuai Feng, Yifan Chen, Yajing Shen, Qihang Su, Yinglei Zhang, Xiang Zhou *, Yu Cheng*,  “Comparison of Two Approaches for the Attachment of a Drug to Gold Nanoparticles and Their Anticancer  Activities”, Molecular Pharmaceutics 2016,  13,3308. (http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.6b00619)
4、Ramin A. Morshed, Megan E. Muroski, Qing Dai, Michelle L. Wegscheid, Brenda Auffinger, Dou Yu, YuHan, Lingjiao Zhang,  Meijing Wu,  Yu Cheng*, Maciej  S. Lesniak*.  “Cell-Penetrating  Peptide-Modified Gold Nanoparticles for the Delivery of Doxorubicin  to  Brain  Metastatic  Breast  Cancer”,  Molecular Pharmaceutics 2016, 13, 1843.(http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.6b00004)
5、Megan E. Muroski, Ramin  A. Morshed, Yu  Cheng*,  Tarun Vemulkar, Rodri, Mansell, Yu Han, Lingjiao  Zhang,  Karen  S.  Aboody, Russell  P.  Cowburn,  Maciej  S.  Lesniak,*  “Controlled  Payload  Release  by Magnetic  Field  Triggered  Neural  Stem  Cell  Destruction  for  Malignant  Glioma  Treatment”,  PLOS  ONE,  2016, 11: e0145129.(http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145129)
6、Yu Cheng,  Megan E.  Muroski, Dorothee  C.M.C.  Petit,  Rhodri  Mansell,  Tarun  Vemulkar,  Ramin  A. Morshed, Yu Han, Irina V.  Balyasnikova, Craig  M.  Horbinski,  Xinlei  Huang,  Lingjiao  Zhang,  Russell  Cowburn,  Maciej  S.  Lesniak,  "Rotating  Magnetic  Field  Induced  Oscillation  of  Magnetic  Particles  for  in  vivo Mechanical Destruction of Malignant Glioma", Journal of Controlled Release 2016, 223: 75.(http://www.sciencedirect.com/science/article/pii/S0168365915302819)
7、Lijie Zhai, Kristen L. Lauing, Alan L. Chang, Mahua Dey, Jun Qian, Yu Cheng, Maciej S. Lesniak, Derek A. Wainwright,  “The Role of IDO in Brain Tumor Immunotherapy”, Journal  of  Neuro-Oncology,  2015, 123,395.  (https://link.springer.com/article/10.1007/s11060-014-1687-8)
8、Hongying Liu, Tennyson L. Doane, Yu Cheng, Feng Lu, Shriya Srinivasana, Jun-Jie Zhu, Clemens Burda, “Control of Surface Ligand Density on PEGylated Gold Nanoparticles  for Optimized Cancer Cell Uptake”, Particle and Particle Systems Characterization , 2015, 32, 197.(http://onlinelibrary.wiley.com/doi/10.1002/ppsc.201400067/full)
9、Yu Cheng, Qing Dai, Ramin Morshed, Xiaobing Fan, Michelle L. Wegscheid, Derek A.  Wainwright, Yu Han,  Lingjiao  Zhang,  Brenda  Auffinger,  Alex  L.  Tobias,  Esther  Rincón,  Bart  Thaci,  Atique  U.  Ahmed, Peter Warnke, Chuan He,  Maciej  S.  Lesniak,  “Blood-Brain  Barrier  Permeable  Gold  Nanoparticles:  An Efficient Delivery Platform for Enhanced Malignant Glioma Therapy and Imaging ”, Small, 2014,  10, 513.(http://onlinelibrary.wiley.com/doi/10.1002/smll.201400654/full)
10、Tennyson Doane, Yu Cheng, Nipun  Sodhi, and Clemens Burda, “NIR Photocleavage of  the Si−C Bond in Axial Si-Phthalocyanines”,The Journal of Physical Chemistry A, 2014, 118,10587.(http://pubs.acs.org/doi/abs/10.1021/jp505656e)
11、Derek A. Wainwright, Alan L. Chang, Mahua Dey, Irina V. Balyasnikova, Chung Kwon Kim, Alex Tobias,  Yu Cheng,  Julius W.  Kim, Jian Qiao,  Lingjiao Zhang,  Yu Han, Maciej S. Lesniak  “Durable  therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4 and PD-L1 in mice with brain tumors”, Clin Cancer Res., 2015, 21,662(http://clincancerres.aacrjournals.org/content/20/20/5290.short)
12、Yu Cheng, Tennyson L.  Doane, Chi-Hung Chuang,  Assem Ziady,  Clemens Burda,“Near  Infrared  Light -Triggered Generation and Release of a Photodynamic Therapy Drug  from  Gold  Nanoparticle  Carriers”,  Small, 2014, 10, 1799.(http://onlinelibrary.wiley.com/doi/10.1002/smll.201303329/full)
13、Michelle M. Wegscheid,  Ramin Morshed,   Yu Cheng,  Maciej S.   Lesniak “The  Art  of   Attraction:  Applications of Multifunctional Magnetic Nanomaterials for Malignant Glioma”,Expert Opin Drug Deliv.  2014, 11(6).(http://www.tandfonline.com/doi/abs/10.1517/17425247.2014.912629)
14、Eun Ji Chung, Yu Cheng  (共同第一作者), Ramin Morshed, Kathryn Nord, Yu Han, Michelle Wegscheid,  Brenda Auffinger, Derek A. Wainwright,  Maciej S. Lesniak, Matthew V. Tirrell. “Fibrin-Binding, Peptide  Amphiphile Micelles for Targeting Glioblastoma”, Biomaterials, 2014, 35,  1249.  (http://www.sciencedirect.com/science/article/pii/S0142961213013082)
15、Yu  Cheng,   Ramin Morshed, Brenda Auffinger, Alex Tobias, Maciej S.   Lesniak.   “Multifunctional  Nanoparticles for Brain Tumor Diagnosis and Therapy”, Adv. Drug Deliv. Rev. 2014, 66, 42. (http://www.sciencedirect.com/science/article/pii/S0169409X13002019)16、Brenda Auffinger,  Ramin Morshed,  Alex L.  Tobias, YuCheng,  Atiqu e U.  Ahmed,  Maciej S.  Lesniak.  “Drug-Loaded  Nanoparticle  Systems  and  Adult  Stem  Cells:  A  Potential  Marriage  for  the  Treatment  of  Malignant Glioma?”, Oncotarget, 2013, 4, 378.(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717302/)
17、Ramin  Morshed,  Yu Cheng,  Brenda  Auffinger,  Michelle  Wegscheid,  Maciej  Lesniak.  “The  potential  of polymeric micelles in the context of glioblastoma multiforme therapy”, Frontiers of Pharmacology , 2013, 4,  157.
18、Ramin  Morshed,  Yu Cheng,  Brenda  Auffinger,  Michelle  Wegscheid,  Maciej  Lesniak.  “The  potential  of polymeric micelles in the context of glioblastoma multiforme therapy”, Frontiers of Pharmacology , 2013, 4,  157.(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874582/)
19、Atique U. Ahmed, Bart Thaci, Alex L. Tobias, Brenda Auffinger, Lingjiao Zhang, Yu Cheng, Chung Kwon Kim, Catherine Yunis, Yu Han, Nikita G. Alexiades, Xiaobing Fan, Karen S. Aboody, Maciej S. Lesniak.  “A  Preclinical  Evaluation  of  Neural  Stem  Cell-Based  Cell  Carrier  for  Targeted  Antiglioma  Oncolytic Virotherapy”, J. Natl. Cancer Inst. 2013, 105, 968.(https://academic.oup.com/jnci/article/105/13/968/957480)
20、Yu Cheng,  Ramin Morshed  ,  Shih-Hsun Cheng,  Alex Tobias,  Brenda Auffinger,  Derek  A.  Wainwright, Lingjiao  Zhang,  Catherine  Yunis,  Yu  Han,  Chin-Tu  Chen,  Leu-Wei  Lo,  Karen  S.  Aboody, Atique U. Ahmed,  Maciej S.  Lesniak.   “Nanoparticle-Programmed  Self-Destructive  Neural  Stem Cells for Glioblastoma Targeting and Therapy”, Small, 2013, 9, 4123.(http://onlinelibrary.wiley.com/doi/10.1002/smll.201301111/full)
21、Brenda  Auffinger,  Bart  Thaci,  Pragati Nigam,  Esther  Rincon,  Yu  Cheng,  Maciej  S.  Lesniak.  “New Therapeutic Approaches  for Malignant Glioma: In Search of the Rosetta Stone.”  F1000 Medicine Report , 2012, 4, 18.(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438652/)
22、Yu  Cheng,  Joseph  D.  Meyers,  Ann-Marie  Broome,  Tennyson  L.  Doane,  Malcolm  E.  Kenney,  Clemens Burda,  James  P.  Basilion  “Addressing  Brain  Tumors  with  Targeted  Gold  Nanoparticles:  A  New  Gold Standard for Hydrophobic Drug Delivery?”, Small, 2011,  7, 2301.(http://onlinelibrary.wiley.com/doi/10.1002/smll.201100628/full)
23、Yu Cheng, Joseph D. Meyers, Ann-Marie Broome, Malcolm E. Kenney, James P. Basilion, Clemens Burda  “Deep Penetration of a PDT Drug into Tumors by Noncovalent Drug-Gold Nanoparticle Conjugates”, J. Am. Chem. Soc. 2011, 133, 2583. (http://pubs.acs.org/doi/abs/10.1021/ja108846h)
24、Yu Cheng, Clemens Burda “Nanoparticle-based Photodynamic Therapy”, Book Chapter of Comprehensive Nanoscience and Technology, 2010, Elsevier.
25、Yu Cheng, Anna C. Samia, Jun Li, Malcolm E. Kenney, Andrew Resnick, Clemens Burda.  “Delivery and  Efficacy of a Cancer Drug as Function of the Bond to the Gold Nanoparticle Surface”, Langmuir  2010, 26,  2248(http://pubs.acs.org/doi/abs/10.1021/la902390d)
26、Tennyson L. Doane, Yu Cheng, Amir Babar, Reghan J. Hill, Clemens Burda “Electrophoretic Mobilities of PEGylated Gold NPs”, J. Am. Chem. Soc. 2010, 132, 15624.(http://pubs.acs.org/doi/abs/10.1021/ja1049093)
27、Yu  Cheng, Anna C. Samia, Joseph D. Meyers, Irene Panagopoulos, Baowei Fei, Clemens Burda “Highly Efficient Drug Delivery with Gold Nanoparticle Vectors for in Vivo Photodynamic Therapy of Cancer”  J. Am. Chem. Soc. 2008, 130, 10643.(http://pubs.acs.org/doi/abs/10.1021/ja801631c)