The
47th International Exhibition of Inventions was successfully held in Geneva,
Switzerland from April 10 to 14, 2019. It is the first time that the TUSM team
participated in the exhibition, and the team of Prof. Xv Guotong won the silver
medal. The Geneva International Invention Exhibition was founded in 1973 by the
World Intellectual Property Organization and the Swiss Federal Government,
which is one of the largest and the most well-known invention exhibitions in
the world. It is also an important international platform for the
transformation of high-tech and industry-university-research cooperation.
There
were thousands of research achievements from universities, enterprises and
scientific research institutions, which came from more than fifty countries and
areas, such as the United States, Germany, France, China etc. What’s more,
national intellectual property offices, Volkswagen, General Electric and other
World Top 500 companies sent their staffs to investigate the cooperation and
transfer of patent rights.
The
exhibition set Gold Medal AFJ Award, Gold Award, Silver Award and Bronze Award,
with a winning percentage of approximately 30%. Prof. Xu Guotong’s team won the
Silver Award. It effectively enhanced TUSM’s international influence of scientific
and technological achievements, fully demonstrated the tremendous vitality of innovation
and scientific research strength, which laid the foundation for promoting the
international cooperation of production, study and research.
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President of the Geneva
International Invention Exhibition came to Tongji University’s booth to express
congratulations.
The
R&D achievement exhibited from Prof. Xu Guotong is “antagonizing glial cell
maturation factors against diabetic retinopathy, diabetic nephropathy and
diabetic osteoporosis”, which is also the research achievement of the “973” National
Major Scientific Research Plan. Since the Glia maturation factor beta (GMFB) is
first isolated from the glial cells in central nervous system, it is highly
expressed during development and expressed less under adult and normal
physiological conditions. Prof. Xu Guotong ‘s research team found that GMFB has
high sensitivity to hyperglycemia and hyperexpression phenomenon in the
early period of experimental diabetic retinopathy (DR), diabetic nephropathy
(DN) and diabetic osteoporosis (DO). GMFB, as a master gene, controls the
release of downstream inflammatory factors including MCP-1, IL-1β, TNFα and
Kim-1. Therefore intervention of GMFB can effectively prevent the occurrence
and development of DR, DN and DO. This research achievement has made a major
breakthrough in the early detection and treatment of diabetic retinopathy,
diabetic nephropathy and diabetic osteoporosis.
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Prof. Lv lixia from Prof.
Xu Guotong’s team made introduction to the jury.